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An analysis of wrist MRIs from participants in the Treatment of Early Aggressive Rheumatoid Arthritis (TEAR) clinical trial indicates that patients continue to show joint inflammation even after two years of early aggressive therapy.
From the College: Student Benefits from Resident Research Preceptorship
Although the ACR Research and Education Foundation offers a number of opportunities to students interested in rheumatology, the Ephraim P. Engleman Endowed Resident Research Preceptorship is a unique opportunity that allows for a much more in-depth learning experience. The purpose of the Engleman Preceptorship is to introduce residents to the specialty of rheumatology by supporting a full-time research experience, with the goal of attracting promising physician–scientists to the field of rheumatology...
From the College: Expression of CD154 Protein Linked to Increased Risk for Developing RA
An ongoing study of key immune system proteins has pinpointed an area associated with increased risk for inflammatory disease and may one day lead to new therapies to control inflammation and rheumatic diseases.
From the College: New ACR and ARHP Leaders Join the Ranks
The ACR is pleased to welcome new and returning leaders to the ACR board of directors and ARHP executive committee who were appointed in November. The following members were selected to serve as the newest members-at-large of the ACR board of directors. Each of them shared what they will bring to the table.
From the College: Naturally Occurring Antibodies May Lead to New RA Therapies
A study published in the Journal of Immunology indicates that naturally occurring antibodies in the human immune system have the capacity to suppress inflammatory responses throughout the body. These antibodies may provide researchers an opportunity to develop new therapies for rheumatoid arthritis (RA) and other inflammatory conditions using similar pathways.
From the College: Research Tracks Possible Benefit of Src-like Adaptor Protein
A study recently submitted for publication has demonstrated that manipulating T-cell receptor complex–mediated signaling can prevent the development of autoimmune arthritis in mice and may lead to new human therapies without the drawbacks associated with existing treatments.
From the College: Research on IL-17 Cytokine May Lead to Novel Therapies for RA
Research in the laboratory of John D. Mountz, MD, PhD, is opening up a whole new field of study in rheumatoid arthritis (RA).
From the College: Unique Meeting Accelerates RA Research
More than 50 rheumatoid arthritis (RA) investigators from across the U.S. recently met in Ft. Worth, Texas, to share information, present data and results from their innovative RA research projects, and brainstorm ways to work more closely together to find a cure for the disease.
Columns: A Goal within Reach
As we are all aware, there is a significant workforce shortage looming over our specialty due to the projected increase of demand for rheumatologic care—an estimated 67 million U.S. adults will have some form of arthritis by 2030. The supply of adult rheumatologists coming into the field will not keep pace. What additional impact healthcare reform and changes in healthcare delivery will have on these projections is not yet clear. It is, in fact, the vision of the ACR to “enhance the value and...
In 1985, patients in wheelchairs and significant joint deformities were still a common sight in waiting rooms in rheumatology practices. The era of early aggressive therapy was only beginning and patients newly diagnosed with rheumatoid arthritis (RA) might have been hospitalized for a week and treated with gold shots. Many patients faced a poor prognosis, with a life of significant pain and disability and possible joint replacement surgery. At the same time, within the ACR—known then as the American...