At the end of the study, patients with active juvenile PsA who received secukinumab had a significantly longer time to flare, with an 85% reduction in the risk of flare (P<.001) compared with those patients who received placebo. Patients with active ERA treated with secukinumab also had a longer time to flare, with a 53% reduction in the risk of flare compared with patients who received placebo. The patients treated with secukinumab had sustained improvements in signs and symptoms up to week 100.
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No new safety signals were identified.
Michele B. Kaufman, PharmD, BCGP, is a freelance medical writer based in New York City and a pharmacist at New York Presbyterian Lower Manhattan Hospital.
- Novartis Cosentyx receives FDA approval for the treatment of children and adolescents with enthesitis-related arthritis and psoriatic arthritis. Novartis AG. 2021 Dec 23.
- Shih Y, Yang Y, Lin C, et al. Enthesitis-related arthritis is the most common category of juvenile idiopathic arthritis in Taiwan and presents persistent active disease. Pediatr Rheumatol Online J. 2019 Aug 23;17(1):58.
- Ruperto N, Foeldvari I, Alexeeva E, et al. Efficacy and safety of secukinumab in enthesitis-related arthritis and juvenile psoriatic arthritis: Primary results from a randomised, double-blind, placebo-controlled, treatment withdrawal, phase 3 study (JUNIPERA). Ann Rheum Dis. 2021;80:201–202.