Also in March, the Rheum After 5 column misidentified the journal for which Joan M. Von Feldt, MD, MSEd, is the editor in chief. She is actually the editor in chief of the Journal of Clinical Rheumatology.
The editors regret these errors.
Philip Seo, MD, MHS | Issue: April 2018 |
Also in March, the Rheum After 5 column misidentified the journal for which Joan M. Von Feldt, MD, MSEd, is the editor in chief. She is actually the editor in chief of the Journal of Clinical Rheumatology.
The editors regret these errors.
The past five years have been busier than usual for the Churg-Strauss syndrome. It was renamed eosinophilic granulomatosis with polyangiitis (EGPA).1 Longitudinal cohorts totaling 484 patients—approximately as many as all previous series combined—were described.2,3 A proposal was advanced to remove and rename a subset in which vasculitis may not be present.4 And shortly after the…
Delving deeper into the nonvasculitis aspects of the disease
Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg-Strauss syndrome or allergic granulomatosis and angiitis, is a rare small- and medium-vessel vasculitis. This disease was first described by American pathologists Jacob Churg and Lotte Strauss in 1951.1 Although the vasculitis is often not apparent in the initial phases of the disease, EGPA can affect any…
Based on the classification system developed by the Chapel Hill Consensus Conference, anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis is defined as a necrotizing vasculitis involving small vessels that is associated with myeloperoxidase (MPO) ANCA or proteinase 3 (PR3) ANCA and displays minimal immune deposits. The mechanism behind the pathogenesis of ANCA-associated vasculitis is not fully…