The human intestinal microbiota is home to more than 1,000 bacterial species, containing approximately 3 million genes, many of which code for functions that have the potential to affect human physiology.1 Smaller numbers of organisms are also present in the skin, upper gastrointestinal tract, female reproductive tract and the oro- and nasopharynx. As tools have…
Search results for: microbiome
Research Provides Insight into Impact of Microbiome on Health, Rheumatic Disease
The microbiome comprises diverse microbial flora, including bacteria, viruses and fungi, that live on mucosal surfaces, predominantly the skin and digestive tract. Microbes evolved billions of years prior to the development of modern Homo sapiens 200,000 years ago; we have always existed with their ubiquitous presence. Despite this, the first microbe was not visualized until…
2015 ACR/ARHP Annual Meeting: Insights into the Microbiome
SAN FRANCISCO—The organisms in the gut are remarkably malleable with diet, dangling the possibility that diseases could potentially be affected by the food that people eat, according to an expert here at the 2015 ACR/ARHP Annual Meeting. Diet Starting with studies of animal feces from zoos and from the wild, in which researchers found that…
Gut-on-a-Chip Provides Insight into Microbiome & Intestinal Inflammation
Researchers have created a microdevice with Caco-2 intestinal epithelial cells to aid in studying the human gut microbiome’s role in homeostasis, immune modulation and pathology. Using this gut-on-a-chip, researchers were able to examine in detail the processes they think result in chronic intestinal inflammation…
The Microbiome’s Role in Inflammatory Arthritis
Despite the relative novelty of the human microbiome as an area of study, a substantial body of evidence has accumulated addressing its potential involvement in the pathogenesis of rheumatic disease. This review article explores the available data in animal and human studies, focusing on the role of the intestinal microbiome in rheumatoid arthritis (RA), psoriatic arthritis (PsA) and the spondyloarthritidies (SpA)…
Oral & Gut Microbiomes Altered in Rheumatoid Arthritis Patients
NEW YORK (Reuters Health)—Patients with rheumatoid arthritis (RA) have alterations in their oral and gut microbiomes that partially normalize with treatment, according to results from a metagenome-wide association study. The microbiota influence metabolic and immune homeostasis, and microbial triggers have been postulated in RA, but little is known about the oral and gut microbiomes of…
Home Microbiome Project Pegs People as Primary Bacteria Vectors
Research suggests humans harbor microbial fingerprint that can be transferred to new indoor spaces
Microbiome Research Provides Clue to Rheumatoid Arthritis
A new study suggests that intestinal expansion of Prevotella copri may be associated with the pathogenesis of RA
The Microbiome
A voyage to (our inner) Lilliput
What Every Clinician Should Know about Ramadan & Intermittent Fasting
Intermittent fasting—defined as alternating between cycles of eating and going without food over a given period of time—has become popular with individuals seeking to lose weight or balance their lifestyle in recent years. During Ramadan (a period based on the Gregorian calendar that changes from year to year), able-bodied Muslims are obligated to observe a…
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