Treating Lupus Nephritis From the College | January 6, 2026 The 2024 ACR Guideline for the Screening, Treatment, and Management of Patients with Lupus Nephritis recommends what approach to the treatment of patients with lupus nephritis? Review the guideline or take the quiz below. For patients with active, new-onset or flare of Class III/IV or Class V lupus nephritis, the 2024 ACR Guideline for the Screening, Treatment, and Management of Patients with Lupus Nephritis includes a conditional recommendation: A. For voclosporin over belimumab in a triple immunosuppressive therapy approach B. For belimumab over voclosporin or other calcineurin inhibitor therapy in a triple immunosuppressive therapy approach C. For daily cyclophosphamide until the flare resolves D. To increase the doses and frequency of all medications until the flare resolves None Time's up