ACR Convergence 2025| Video: Rheum for Everyone, Episode 26—Ableism

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Lupus Nephritis FocusRheum

Dr. Alarcón

Dr. Alarcón

Both systemic lupus erythematosus and lupus nephritis reduce a person’s life expectancy, with SLE cutting an average of 12.4 years off a person’s life expectancy and lupus nephritis reducing life expectancy by another 2.7 years, according to a study by Mok et al. Below, lupus expert Graciela S. Alarcón, MD, MPH, MACR, highlights some of the many abstracts on research into LN presented at ACR Convergence 2025. Also, review our collection of articles on the topic. Features are added often, so check back frequently.

FEATURED ARTICLE: Lupus Nephritis: A Serious Manifestation of Systemic Lupus Erythematosus

Research, Case Reports & More

Complications: Renal Arteriosclerosis in Patients with Lupus Nephritis

November 21, 2025

Renal arteriosclerosis is common in patients with lupus nephritis and occurs two decades earlier than it does in people without the condition, say investigators in a study that examined the prevalence of renal arteriosclerosis in patients with lupus nephritis compared with healthy controls.1 The finding suggests that renal arteriosclerosis could be used as a biomarker…

Secrets & Pearls of Rheumatology at ACR Convergence 2025

November 12, 2025

Two clinical diagnosticians presented their pearls of wisdom for clinical rheumatologists to take forward when managing patients from the clinics to the hospital wards.

3 AC&R Study Summaries: RA & Frailty, Hydroxychloroquine Can Protect Kidneys in Lupus Nephritis, & PT for Knee OA

November 11, 2025

Research on PT for knee OA, HCQ’s protective role in lupus nephritis & the link between RA disease activity & frailty.

Lupus Nephritis from Bench to Bedside

November 5, 2025

Urinary biomarkers may have the potential to detect early treatment responses or failures in patients with lupus nephritis, according to Andrea Fava, MD. He and other experts discussed the latest research into lupus nephritis and how apply the recent ACR guideline to refractory cases.

Let’s Discuss: Insights from the ACR Convergence 2025 Review Course

October 27, 2025

The Review Course at ACR Convergence 2025 provided a comprehensive update for practitioners. Highlights from the sections on SLE and lupus nephritis, inflammatory brain diseases, drug management of rheumatic diseases and mimics of inflammatory myopathies.

Study: Reducing Cardiovascular Risks Helps Lupus Patients

October 8, 2025

Long-term remission & control of CVD risk factors can reduce the risk of atherosclerosis in lupus; triple APL positivity raises the risk of CVD, study finds.

Lupus Nephritis: A Brief Review

May 15, 2025

Among patients with sys­temic lupus erythematosus (SLE), lupus nephritis is one of the more common health problems and a leading cause of mortality. In adults with SLE, as many as five of 10 will develop kidney disease. In children with lupus, eight of 10 will develop kidney disease.1 Lupus nephritis appears to be more prevalent…

lupus nephritis, showing wire loop and hyaline thrombi, PAS stain, magnification 400x, photo under microscope

Lupus Nephritis Guideline Encourages Triple Therapy

November 24, 2024

Screening recommendations, triple therapy and more—here are insights into the upcoming ACR guideline for the care and treatment of patients with lupus nephritis.

Autoantibodies Illuminate Lupus Nephritis

October 28, 2024

Fava et al. investigated longitudinal autoantibody profiles in patients with lupus nephritis (LN) to define serological biomarkers of histologic class. They found that baseline levels of anti-C1q and anti-double-stranded DNA antibodies may serve as noninvasive biomarkers of proliferative LN and anti-C1q antibodies may predict complete response.

Lupus Update: Findings from the Latest Phase 3 Clinical Trials

October 11, 2024

Two new treatment studies among patients with systemic lupus erythematosus and lupus nephritis had promising results.

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