2015 ACR/ARHP Annual Meeting: Insights into the Microbiome

He said it’s not known yet whether the mechanisms his lab has found are systemic or confined to the gut.

“Worm infections can block MS-like disease in mice,” he said. “The same worm can regulate asthma-like disease. But we do not know if worms trigger the same immune regulatory mechanisms in all tissues.”

Thomas R. Collins is a medical writer based in Florida.

References

1. David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014 Jan 23;505(7484):559–563.
2. Devkota S, Wang Y, Musch MW, et al. Dietary-fat induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice. Nature. 2012 Jul 5;487(7405):104–108.
3. Carmody RN, Gerber GK, Luevano JM, et al. Diet dominates host genotype in shaping the murine gut microbiota. Cell Host Microbe. 2015 Jan 14;17(1):72–84.