Polymyositis-Dermatomyositis Tied to Arrhythmias in Young, Middle-Aged Adults

“Given the supposed key role of inflammatory activation in the pathogenesis of arrhythmias, lowering the inflammatory burden through an increasingly tight control of disease activity may represent the most effective intervention to reduce arrhythmic risk in these patients,” Dr. Lazzerini, who wasn’t involved in the study, says by email.

“Intriguingly, these considerations could be more generally applicable to all the diseases characterized by chronic systemic inflammation and could help elucidate the link between subclinical low-grade chronic inflammation and arrhythmic risk in apparently healthy individuals of the general population,” Dr. Lazzerini says.

Reference

Naaraayan A, Meredith A, Nimkar A, et al. Arrhythmia prevalence among patients with polymyositis-dermatomyositis in the United States: An observational study. Heart Rhythm. 2021 May 26;S1547-5271(21)00456-2. Online ahead of print.

Identifying and treating cardiac involvement in systemic sclerosis can be a challenge

Without a single set of diagnostic criteria for identifying polymyositis, dermatomyositis, or myositis and scant evidence-based therapeutic guidelines, these rare muscle diseases can be hard to manage

Since it was first reported in 1916, a correlation between inflammatory myopathies and cancer has been noted in several studies. Population studies have confirmed this relationship, and the phrase cancer-associated myopathy has entered the vernacular. Over the past decade, research efforts have shifted toward revealing associations between autoantibodies and clinical phenotypes. One subset of auto-antigens…

NEW YORK (Reuters Health)—Psoriasis is linked to a higher risk for arrhythmia, independent of classic cardiovascular (CV) risk factors, according to a study from Taiwan. “In my practice, arrhythmia as comorbidity is discussed during patient consultation along with other comorbidities,” said senior author Dr. Tsen-Fang Tsai of the Department of Dermatology at National Taiwan University…

The Heart-SCC Puzzle

Inflammatory Myopathies Difficult to Diagnose, Treat

Cancer-Associated Myositis: A Case Report & Review of the Literature

Psoriasis, Psoriatic Arthritis Linked with Arrhythmia

Related Articles