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Pulmonary Compromise Leads to Relapsing Polychondritis Diagnosis

Marcela A. Ferrada, MD, Anjali Takyar, MD, & James D. Katz, MD  |  Issue: October 2018  |  October 18, 2018

Relapsing polychondritis can affect not only the airways, but also the lung parenchyma. Early recognition and treatment of airway involvement can help prevent end organ damage.


Marcela A. Ferrada, MD, is a rheumatology fellow at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Bethesda, Md.

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Anjali Takyar, MD, works at the Crozer-Chester Medical Center, Upland, Pa.

James D. Katz, MD, works at NIAMS, Bethesda, Md.

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Acknowledgment

This review was supported in part by the Intramural Research Program of the National Institute of Arthritis and Musculo­skeletal and Skin Diseases of the National Institutes of Health.

References

  1. Ferrada MA, Grayson PC, Banerjee S, et al. Patient perception of disease-related symptoms and complications in relapsing polychondritis. Arthritis Care Res (Hoboken). 2018 Aug;70(8):1124–1131.
  2. Michet CJ, Jr, McKenna CH, Luthra HS, et al. Relapsing polychondritis. Survival and predictive role of early disease manifestations. Ann Intern Med. 1986 Jan;104(1):74–78.
  3. McAdam LP, O’Hanlan MA, Bluestone R, et al., Relapsing polychondritis: Prospective study of 23 patients and a review of the literature. Medicine (Baltimore). 1976 May;55(3):193–215.
  4. Pearson CM, Kline HM, Newcomer VD. Relapsing polychondritis. N Engl J Med. 1960 Jul 14;263:51–58.
  5. Hughes RA, Berry CL, Seifert M, et al. Relapsing polychondritis. Three cases with a clinico-pathological study and literature review. Q J Med. 1972 Jul;41(163):363–380.
  6. Hazra N, Dregan A, Charlton J, et al. Incidence and mortality of relapsing polychondritis in the UK: A population-based cohort study. Rheumatology (Oxford). 2015 Dec;54(12):2181–2187.
  7. Ernst A, Rafeq S, Boiselle P, et al. Relapsing polychondritis and airway involvement. Chest. 2009 Apr;135(4):1024–1030.
  8. Burlew BP, Lippton H, Klinestiver D, et al. Relapsing polychondritis: New pulmonary manifestations. J La State Med Soc. 1992 Feb;144(2):58–62.

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