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An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

Recent Trials Investigated Targeted Therapies for Systemic Sclerosis

  |  Issue: May 2019  |  

Mary Beth Nierengarten is a freelance medical journalist based in Minneapolis.

References

  1. Khanna D, Spino C, Bush E, et al. Abatacept vs. placebo in early diffuse cutaneous systemic sclerosis—results of a phase 2 investigator initiated, double-blind, placebo-controlled, multicenter, randomized controlled trial study (abstract 900). Arthritis Rheumatol. 2018;70(suppl 10).
  2. Khanna D, Lin CJF, Kuwana M, et al. Efficacy and safety of tocilizumab for the treatment of systemic sclerosis: Results from a phase 3 randomized controlled trial (abstract 898). Arthritis Rheumatol. 2018;70(suppl 10).
  3. Distler O, Allanore Y, Denton CP, et al. Riociguat in patients with early diffuse cutaneous systemic sclerosis: A randomized, double-blind, placebo-controlled phase IIb study (RISE-SSc) (abstract 903). Arthritis Rheumatol. 2018;70(suppl 10).
  4. Khanna D, Denton CP, Jahreis A, et al. Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): A phase 2, randomised, controlled trial. Lancet. 2016 Jun 25;387(10038):2630–2640.
  5. Kolstad KD, Li S, Steen V, et al. Long-term outcomes in systemic sclerosis-associated pulmonary arterial hypertension from the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma Registry (PHAROS). Chest. 2018 Oct;154(4):862–871.
  6. Frost A, Badesch D, Gibbs JSR, et al. Diagnosis of pulmonary hypertension. Eur Respir J. 2019 Jan 24;53(1).
  7. Sullivan K, Pinckney A, Goldmuntz E, et al. Myeloablative autologous hematopoietic stem cell transplantation for severe scleroderma: Long-term outcomes 6–11 years after entry on a randomized study comparing transplantation and cyclophosphamide (abstract 1820). Arthritis Rheumatol. 2018;70(suppl 10).

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