Despite the innovations of new biologics and disease-modifying anti-rheumatic drugs, a large unmet need remains for patients with rheumatic autoimmune disease. Treatment remains limited for many conditions, including for conditions with a dim prognosis, such as systemic sclerosis.1 One promising treatment avenue is hematopoietic stem-cell transplantation (HSCT). Here, we provide background on HSCT for severe…
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Despite our best efforts and modern interventions, we still have patients in the intensive care unit with organ failure. Although renal failure can be mitigated by dialysis, patients with cardiac or respiratory failure secondary to active autoimmune disease raise difficult clinical and ethical issues. Two recent cases, both with organ failure, led us to examine…
Samuel Strober was born on May 8, 1940, in Brooklyn, N.Y., the oldest son of Lee and Julius Strober. Sam attended Public School 92 in Brooklyn and Stuyvesant High School in Manhattan, and graduated from Columbia College, New York, in 1961, and Harvard Medical School, Boston, in 1966. While in high school, Sam won a…