Video: Every Case Tells a Story| Webinar: ACR/CHEST ILD Guidelines in Practice

An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

  • Conditions
    • Axial Spondyloarthritis
    • Gout and Crystalline Arthritis
    • Myositis
    • Osteoarthritis and Bone Disorders
    • Pain Syndromes
    • Pediatric Conditions
    • Psoriatic Arthritis
    • Rheumatoid Arthritis
    • Sjögren’s Disease
    • Systemic Lupus Erythematosus
    • Systemic Sclerosis
    • Vasculitis
    • Other Rheumatic Conditions
  • FocusRheum
    • ANCA-Associated Vasculitis
    • Axial Spondyloarthritis
    • Gout
    • Psoriatic Arthritis
    • Rheumatoid Arthritis
    • Systemic Lupus Erythematosus
  • Guidance
    • Clinical Criteria/Guidelines
    • Ethics
    • Legal Updates
    • Legislation & Advocacy
    • Meeting Reports
      • ACR Convergence
      • Other ACR meetings
      • EULAR/Other
    • Research Rheum
  • Drug Updates
    • Analgesics
    • Biologics/DMARDs
  • Practice Support
    • Billing/Coding
    • EMRs
    • Facility
    • Insurance
    • QA/QI
    • Technology
    • Workforce
  • Opinion
    • Patient Perspective
    • Profiles
    • Rheuminations
      • Video
    • Speak Out Rheum
  • Career
    • ACR ExamRheum
    • Awards
    • Career Development
  • ACR
    • ACR Home
    • ACR Convergence
    • ACR Guidelines
    • Journals
      • ACR Open Rheumatology
      • Arthritis & Rheumatology
      • Arthritis Care & Research
    • From the College
    • Events/CME
    • President’s Perspective
  • Search

Research Advances Continue in the Fight Against Lupus

Larry Beresford  |  Issue: June 2019  |  June 17, 2019

In Conclusion

Older and conventional therapies used with lupus patients often suppress the immune system overall, with a greater risk for negative side effects, Dr. van Vollenhoven said. The newer drugs, mostly biologics or targeted therapies, aim to selectively stop some aspect of immune response. Some are very specific in their target. Novel and slightly unconventional approaches to solving this puzzle hold particular promise, he noted.


Larry Beresford is a medical journalist in Oakland, Calif.

ad goes here:advert-1
ADVERTISEMENT
SCROLL TO CONTINUE

References

  1. Van Vollenhoven R, Hahn BH, Tsokos GC, et al. Ustekinumab targets a novel mechanism of action to treat patients with systemic lupus erythematosus. Abstract presentation at 13th International Congress on Systemic Lupus Erythematosus, San Francisco, 2019 Apr 6.
  2. Houssiau F, Thanou A, Mazur M, et al. Ifnα-kinoid in systemic lupus erythematosus (SLE): Results from a phase 2b, randomized, placebo-controlled study. Abstract presentation at 13th International Congress on Systemic Lupus Erythematosus, San Francisco, 2019 Apr 6.
  3. Silk ME, Wallace DJ, Furie RE, et al. Baricitinib in patients with systemic lupus erythematosus: Results from a phase 2, randomized, double-blind, placebo-controlled study. Abstract presentation at 13th International Congress on Systemic Lupus Erythematosus, San Francisco, 2019 Apr 6.
  4. Mok CC. Calcineurin inhibitors in the management of SLE. Abstract presentation at 13th International Congress on Systemic Lupus Erythematosus, San Francisco, 2019 Apr 6.
  5. Onno Teng YK. Combining B-cell targeted therapies in SLE. Abstract presentation at 13th International Congress on Systemic Lupus Erythematosus, San Francisco, 2019 Apr 6.
  6. Rovin BH, Furie R, Latinis K, et al. Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The Lupus Nephritis Assessment with Rituximab study. Arthritis Rheum. 2012 Apr;64(4):1215–1226.
  7. BEAT Lupus Trial.
  8. Teng YKO, Bruce IN, Diamond B, et al. Phase III, multicentre, randomised, double-blind, placebo-controlled, 104-week study of subcutaneous belimumab administered in combination with rituximab in adults with systemic lupus erythematosus (SLE): BLISS-BELIEVE study protocol. BMJ Open. 2019 Mar 20;9(3):e025687.
  9. Oates JC, D’Cruz D, Maksimowicz-McKinnon K, et al. Efficacy and safety of belimumab in patients of black race with systemic lupus erythematosus: Results from the EMBRACE study. Abstract presentation at 13th International Congress on Systemic Lupus Erythematosus, San Francisco, 2019 Apr 6.

Page: 1 2 3 | Single Page
Share: 

Filed under:ConditionsMeeting ReportsSystemic Lupus Erythematosus Tagged with:International Congress of Lupustargeted immune modulatortargeted therapy

Related Articles

    Genomics Research Highlighted at Lupus Conference

    June 17, 2019

    SAN FRANCISCO—The challenges of trying to solve the puzzle of lupus, in light of its broad heterogeneity of symptoms, manifestations in clinical involvement and treatment response, and the sheer complexities of the immune system, are driving researchers into ever more elaborate investigations of how the immune system functions in lupus patients. Genetic, transcriptomic and epigenetic…

    New Developments in Rheumatoid Arthritis Treatment; Personalized Therapy for Patients Ultimate Goal

    August 11, 2016

    SAN FRANCISCO—Considerable progress has been made in the treatment and management of rheumatoid arthritis (RA) in the past two decades, with rheumatologists now able to manage the effects of this chronic, debilitating condition for most of their patients, according to Ronald van Vollenhoven, MD, director of the Amsterdam Rheumatology and Immunology Center (ARC) in the…

    Antiphospholipid Antibody Testing Update

    January 13, 2012

    Successes, challenges, and controversies of diagnostic methods for APS

    Désirée Van Der Heijde, MD, PhD, a Key Driver of Treatment Advances

    May 8, 2012

    Dr. van der Heijde learned early in her career that serendipity often plays a role in clinical research and treatment advances.

  • About Us
  • Meet the Editors
  • Issue Archives
  • Contribute
  • Advertise
  • Contact Us
  • Copyright © 2025 by John Wiley & Sons, Inc. All rights reserved, including rights for text and data mining and training of artificial technologies or similar technologies. ISSN 1931-3268 (print). ISSN 1931-3209 (online).
  • DEI Statement
  • Privacy Policy
  • Terms of Use
  • Cookie Preferences