Triple Therapy with Methotrexate Effective, Cheaper in RA

“Many patients, particularly in the U.S., proceed to biologic therapy after failure of methotrexate alone. Our review challenges this approach,” Dr. Hazlewood told Reuters Health.

“Any systematic review summarizes average treatment effects,” he continued. “These choices are often complex and need to be tailored to a patients’ disease activity and preferences. This should occur through a shared discussion with the patient and his or her rheumatologist.”

The Arthur J.E. Child chair in rheumatology outcomes research partially supported this research.