A post-hoc analysis of data from two clinical trials showed that nano-encapsulated sirolimus with pegylated-adricase (NASP) may be effective for promoting tophus resolution and lowering serum uric acid in patients with uncontrolled gout.
RA Research Presented at ACR Convergence 2025 in Focus
This synopsis of research into rheumatoid arthritis highlights key areas presented at ACR Convergence 2025, including strategies to delay or prevent RA, emerging mechanisms of action in RA treatment, and the growing role of AI in advancing RA research and clinical care.
The Great Pediatric Debate—Corticosteroids in SLE: Slay or Stay?
Long-term use of corticosteroids is associated with numerous adverse effects, particularly in children, but guidance is lacking on how to manage low-dose prednisone in clinically quiescent disease. In The Great Debate at ACR Convergence 2025—Corticosteroids in Pediatric SLE: Slay or Stay, two pediatric lupus experts took to the stage to explore this important topic.
The Great Debate: Ultrasound vs. Temporal Artery Biopsy in Giant Cell Arteritis
In the ACR Convergence 2025 session, Great Debate: Ultrasound vs. Temporal Artery Biopsy in Giant Cell Arteritis, two vasculitis experts went head to head to determine the ideal first test in the diagnosis GCA: ultrasound or biopsy.
Insights into SLE & Lupus Nephritis From the 2025 Review Course
Review expert strategies & clinical pearls for managing SLE & lupus nephritis. Get therapeutic updates from the ACR’s 2025 Review Course.
Lupus Nephritis: A Serious Manifestation of Systemic Lupus Erythematosus
This review highlights some of the many abstracts on lupus nephritis research presented at ACR Convergence 2025. They demonstrate advances made on early recognition of the condition, as well as offering some hope in terms of achieving better outcomes.
Reflections on B Cells in SLE & Lupus Nephritis
At the Dubois Memorial Lecture presented at ACR Convergence 2025, Shaun Jackson, MD, PhD, discussed the evolving understanding of the role of B cells in SLE.
A Liquid Biopsy for Lupus Nephritis?
Urine biomarkers have the potential to change how lupus nephritis is managed, serving as a noninvasive means of early detection, assessing treatment response and more.
The ACR Releases New Lupus Nephritis Guideline
At a session of ACR Convergence 2024, speakers shared key elements of the new guideline on the screening, treatment and overall management of lupus nephritis in children and adults.1 This guideline attempts to balance the risks of medication side effects with the important goal of preserving kidney function. This is the ACR’s first lupus guideline…
Neutrophilic Inflammation in Spondyloarthritis
CHICAGO—In the basic science session, Beyond NETs: Alternative Roles of Neutrophils in Spondyloarthritis, neutrophils are explored as a common pathophysiologic thread among the spondyloarthropathies. In this two-part talk, Dennis McGonagle, PhD, professor of investigative rheumatology at the Leeds Institute of Rheumatic and Musculoskeletal Medicine at St James Hospital, Leeds, England, opens by examining the role…
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