Anderson et al. studied genetic data on more than 190,000 participants and found 23 who had genetic variants in the UBA1 gene, which is associated with VEXAS.

ACR Image Competition 2025 Results, Part 2—People’s Choice & South Asia Regional Winner
Every year, the ACR conducts a case-based image competition. Images are submitted for peer review. The winning images are displayed at ACR Convergence, and winners receive other benefits as well. In October 2025, annual meeting attendees voted on their favorite presentation, selecting the image case from South Asia, presented by Sarath Chandra Mouli Veeravalli, and…

How to Manage Patients with Chronic Low Back Pain
Because back pain is a chronic condition for many patients, rheumatologists should increase their understanding of the common problems of the lumbar spine.

ACR Image Competition 2025 Results, Part 1—Best Overall
Every year, the ACR conducts a case-based image competition. Images are submitted for peer review. The winning images are displayed at ACR Convergence and winners receive other benefits, as well. This year, the overall winning images were submitted by Madhuri Challa, MD, of Hyderabad, Telangana, India. Presentation These are the representative clinical and radiological images…

Prednisone or Methotrexate for Pulmonary Sarcoidosis?
The recently released PREDMETH study results indicate that methotrexate can be considered a real alternative to prednisone for patients with pulmonary sarcoidosis.

First ACR Guidance Statement for VEXAS Released
VEXAS is a recently identified rare genetic disorder associated with somatic mutations in the UBA1 gene. Given the variability in disease presentation & the limited number of studies to date, an international multidisciplinary panel of VEXAS experts was convened to provide guidance to healthcare providers on the condition’s management. We spoke to experts on the panel about the resulting guidance document.

Secrets & Pearls of Rheumatology at ACR Convergence 2025
Two clinical diagnosticians presented their pearls of wisdom for clinical rheumatologists to take forward when managing patients from the clinics to the hospital wards.

Let’s Discuss Part 2: More Insights from the ACR Convergence 2025 Review Course
The Review Course at ACR Convergence 2025 provided a comprehensive update for practitioners. Highlights from the sections on cutaneous manifestations of rheumatic diseases, gout, macrophage activation syndrome and vasculitis are presented here.

Let’s Discuss: Insights from the ACR Convergence 2025 Review Course
The Review Course at ACR Convergence 2025 provided a comprehensive update for practitioners. Highlights from the sections on SLE and lupus nephritis, inflammatory brain diseases, drug management of rheumatic diseases and mimics of inflammatory myopathies.

Insights into Mechanisms of Anti-Inflammatory Response to Exercise
A recent Proceedings of the National Academy of Sciences study found that high-intensity aerobic exercise may reduce the release of cell-free DNA & tamp down inflammation over time.
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