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Research Rheum

Foundation Earns Coveted 4-Star Rating from Charity Navigator for 10th Consecutive Year

From the College  |  March 18, 2019

The Rheumatology Research Foundation’s strong financial health and commitment to accountability and transparency have earned yet another four-star rating from Charity Navigator, America’s largest independent charity evaluator. This is the 10th consecutive time the Foundation has earned this top distinction. Only 1% of charities have ever received 10 consecutive four-star evaluations, indicating the Foundation outperforms…

New Study: Does Urate-Lowering Therapy Reduce Gout-Patient Mortality?

New Study: Does Urate-Lowering Therapy Reduce Gout-Patient Mortality?

Ruth Jessen Hickman, MD  |  March 18, 2019

Results of a recent study in Arthritis & Rheumatology fail to clarify whether urate-lowering therapies may potentially reduce mortality risk in patients with gout.1 The study also underscores the fact that many physicians are not following the ACR guideline to help their patients achieve target serum urate levels. Partly because of this, it remains unclear…

Research Suggests Th17 Cells Have Microbiota-Dependent Role in RA

Kathy Holliman  |  March 18, 2019

A growing body of research is elucidating the role of intestinal microbiota in several auto­immune diseases, including rheumatoid arthritis (RA). Research published in December 2018 Arthritis & Rheumatology increases our understanding of the “extent and nature of mucosal immune activation during preclinical arthritis.”1 The research objective, according to the report, was to “dissect intestinal mucosal immune…

Rheumatoid Arthritis Risk Lower Among Smokers Who Quit

Lisa Rapaport  |  March 5, 2019

(Reuters Health)—Adults who quit smoking decades ago may have a lower risk of rheumatoid arthritis (RA) than people who gave up cigarettes more recently, a U.S. study suggests. Smoking has long been linked to an increased risk of RA, and quitting can reduce this risk. But the new study offers fresh evidence that years of…

Tainted Research Repeatedly Re-Used to Assess Drug Effectiveness

Gene Emery  |  March 5, 2019

(Reuters Health)—A new study shows how fake news—specifically, information about scientific research that may be tainted by fraud—keeps getting spread through the medical literature, misleading doctors about the safety and effectiveness of the drugs they prescribe. At issue is the failure of medical journals to flag research that’s been identified by the U.S. Food and…

Duration & Treatment of Musculoskeletal Symptoms of Immunotherapy-Induced Arthritis

Arthritis Care & Research  |  March 4, 2019

A new case series outlines the treatment and duration of symptoms of 10 patients experiencing the musculoskeletal manifestations of immune-related adverse events. Researchers found these symptoms may last for more than a year, but can generally be treated with low to moderate doses of corticosteroids…

Mortality Trends in Lupus Nephritis

Arthritis & Rheumatology  |  February 28, 2019

According to results of a recent study of all-cause and cause-specific mortality trends of end-stage renal disease due to lupus nephritis from 1995 to 2014, the all-cause premature mortality rate improved among white, African American and Hispanic patients, with reduced risk of death from CVD and infection. Jorge et al. observed a 32% reduction in mortality. This improved survival may be explained by a combination of improvements in the management of ESRD and of underlying SLE…

Rheumatology Research Foundation Fuels Pipeline of Next-Gen Providers

From the College  |  February 18, 2019

One aspect of the Rheumatology Research Foundation’s work is recruiting more people into the field, and it starts by building interest in rheumatology among the best and brightest medical and graduate students. The Foundation is fueling the pipeline of rheumatology professionals by supporting students, residents and fellows in a number of ways, such as with…

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Why & How Our Biologic Drug Discussion with Patients Should Evolve

Paul H. Caldron, DO, PhD, MBA, & John R.P. Tesser, MD  |  February 17, 2019

As we turn the corner on the second decade of biologic use for rheumatic disorders, a reappraisal of approach in our communication with patients is due. In practice, the impact these agents have on patients’ lives justifies the friction rheumatologists face when connecting patients to them. You can understand why older rheumatologists who apprenticed on…

Walking Ability of OA Patients Linked to Cardiovascular Risk

Arthritis Care & Research  |  February 5, 2019

New research explores the association of the ability to walk and the risk of cardiovascular disease in OA patients compared with the general population. During the study, researchers recorded a six-minute walking distance and measured arterial stiffness of participants. The results: Even among younger people, OA patients could not walk as far as those in the general population. Also, arterial stiffness was inversely associated with walking distance, suggesting walking is important to the cardiovascular risk profile of OA patients…

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