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Research Rheum

3 AC&R Study Summaries: Fractures in Patients with SSc, Clinical Response in JIA, & TV & the Public Perception of Gout

Arthritis Care & Research  |  August 13, 2023

Fractures in Patients with SSc By Zsuzsanna McMahan, MD, MHS Why was this study done? To minimize disability due to systemic sclerosis (SSc), it’s important to prevent and manage complications. Many SSc complications and related medications may increase the risk for osteoporosis and fracture. We sought to identify modifiable risk factors for fracture in patients…

Wired: Tech-Based Strategies for Engaging Patients in Research

Jason Liebowitz, MD, FACR  |  June 27, 2023

Artificial intelligence, social media, mobile apps—different technologies can be used to connect with and benefit rheumatology patients. During a session of the 2023 Pediatric Rheumatology Symposium, Dr. Jonathan Hausmann discussed the use of technology in research to improve patient recruitment and engagement, collect data and more.

Thick Skin & Solid Research: Necessary Ingredients for Publishing Success

Vanessa Caceres  |  June 1, 2023

Scientific publishing requires a commitment to clear writing, concise narratives and a willingness to accept feedback. Daniel Solomon, MD, editor-in-chief of Arthritis & Rheumatology, provides insights into his experiences.

RA Disease Activity & Alcohol Consumption Habits

Arthritis & Rheumatology  |  May 30, 2023

Past studies have suggested that patients with rheumatoid arthritis (RA) who consume a moderate amount of alcohol may experience lower disease activity and higher quality of life than non-drinkers. In this study, Alfredsson, et al. confirmed earlier studies’ claims that alcohol consumption reduces disease activity in a dose-dependent manner, and also indicated that patients who stopped drinking post-baseline experienced worsened disease activity, more pain and a lower quality of life.

New Study Probes Hydroxychloroquine Adherence During Pregnancy

Antonia Chan & Julia F. Simard, ScD  |  May 11, 2023

Hydroxychloroquine (HCQ) is nearly universally recommended for pregnant patients with systemic lupus erythematosus (SLE) to reduce lupus disease activity and adverse outcomes in pregnancy.1-3 Yet despite strong evidence supporting its benefits, HCQ appears underutilized, with several studies suggesting fewer than half of all women with lupus take this medication during pregnancy.4 How accurately these results…

2 AC&R Study Summaries: Racial Disparities in Lupus Trials & Post-Discharge Follow-Up in Lupus

Arthritis Care & Research  |  May 9, 2023

Racial Disparities in Lupus Clinical Trial Participation By Saira Z. Sheikh, MD Why was this study done? Lupus disproportionately affects Black and Latino populations, particularly women in childbearing years. Clinical trials of patients with lupus can advance the development of therapeutics and access to better treatments, as well as improve health outcomes for patients. However,…

A Conversation with Rheumatology Research Foundation VP Liana Fraenkel, MD, MPH

Leslie Mertz, PhD  |  May 5, 2023

Liana Fraenkel, MD, MPH, likes to fix things, and the dynamic and challenging field of rheumatology always has room for improvement. That mindset has led her down some interesting paths as a researcher and healthcare provider, and as vice president of the Rheumatology Research Foundation. Dr. Fraenkel was a rheumatologist and researcher at the Yale…

Platelets in the Pathogenesis of SLE

Arthritis & Rheumatology  |  April 24, 2023

In a study, El Bannoudi et al. found that platelets contribute to the pathogenesis of SLE by secreting the proinflammatory platelet-associated lectin, galactoside-binding, soluble 3 binding protein (LGALS3BP), which also represents a novel biomarker of SLE clinical activity.

Anti-P. copri Antibody Responses in Patients with RA

Arthritis & Rheumatology  |  March 30, 2023

Background & Objectives Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with immune responses to the patient’s own antigens and characterized by inflammation and substantial joint destruction. Prevotella copri, a gut commensal bacterium, has been reported to be an immune-relevant organism in individuals with RA. This study sought to evaluate antibody responses to anti-P….

Long COVID: Experts Weigh in on Increasingly Common Syndrome

Ruth Jessen Hickman, MD  |  March 16, 2023

A minority of patients experience lingering symptoms after infec­tion with SARS-CoV-2, similar to some other previously known post-infection syndromes. Although we are just beginning to understand the differ­ent presen­tations, pathophysiology, risk factors, prognosis and treatment of long COVID, rheumatologists can play a leader­ship role in managing patients with the illness and contributing to this important research…

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