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Research Rheum

FOCIS 2015: Research Increases Understanding of Lupus, RA

Catherine Kolonko  |  October 13, 2015

The field of rheumatology took center stage when a handful of speakers discussed trends and research during a disease-oriented session of the 2015 Federation of Clinical Immunity Societies (FOCIS 2015) conference held in San Diego in June. Neutrophils in SLE Mariana Kaplan, MD, chief of Systemic Autoimmunity Branch at the National Institute of Arthritis and…

Rheumatology Research Foundation Reaches 30-Year Milestone

E. William St.Clair, MD, & David R. Karp, MD, PhD  |  October 13, 2015

For 30 years, the Rheumatology Research Foundation has been working to advance research and training to improve the health of people with rheumatic diseases. The past three decades are replete with the achievement of significant milestones and extraordinary accomplishments. Funding Research, Training The Foundation’s efforts began in 1985 when it was established by the ACR….

How Hospitals Rank in Treating Childhood-Onset SLE

Richard Quinn  |  October 6, 2015

A recent study of how medical facilities in three countries meet minimum care standards for patients with childhood-onset systemic lupus erythematosus found a wide variation in quality of care…

IL-26 Plays Antimicrobial Role in Immune Response

Lara C. Pullen, PhD  |  September 28, 2015

Researchers determined IL-26 serves as a potent antimicrobial that promotes the immune sensing of both bacterial and host cell death…

Connective Tissue Disorders Lack Societal Concern, Financial Support

Simon M. Helfgott, MD  |  September 15, 2015

“Love is the bone and sinew of my curse.” —Sylvia Plath Cutting the Cord Here’s the problem: No one grows up wanting to seek the cure for bursitis—or tendonitis or just about any of the other seemingly mundane maladies afflicting our body’s scaffolding. Meniscal tears, fasciitis, tendinopathies—the list is endless. Chances are, your college essay…

FOCIS 2015: TET Protein Regulation May Provide Insights for Cancer Treatment

Catherine Kolonko  |  September 15, 2015

A presentation given during FOCIS 2015, the 15th annual meeting of the Federation of Clinical Immunity Societies in June 2015 in San Diego, focused on advances in stem cell research related to treatment of cancer and the function that particular enzymes play in disease. Anjana Rao, PhD, professor at the La Jolla Institute for Allergy…

Peripheral Nerve Regeneration Insights

Lara C. Pullen, PhD  |  September 14, 2015

A recent investigation provides new details on how macrophages, endothelial cells and Schwann cells coordinate to heal peripheral nerve damage…

Can Childhood Fitness Predict Adult Knee Problems or OA?

Arthritis Care & Research  |  September 8, 2015

An Australian study found an association between child physical performance measures and adult knee structures. The data, collected from three points in participants’ lives, revealed a link between childhood activity and adult tibial cartilage volume and bone area.

Can We Get Closer to a Cure for RA?

Marc Feldmann & Ravinder N. Maini  |  September 1, 2015

Despite new therapeutics, progress for RA patients has virtually stalled over the past 10 years. In this article, the authors discuss many options to advance to a cure and the evidence for them, including the combination of low-dose methotrexate and anti-TNF; targeting angiogenesis and tissue damage pathways directly; antigen-specific therapy; potential combination of TNF and IL17 blockade; and targeting inhibitory receptors and regulatory T cells.

EULAR 2015: RA Research Shows Imperfect Guidelines, Suggests Strategies with Biologics

Thomas R. Collins  |  August 17, 2015

ROME, Italy—Even with classification criteria that have been updated and refined over time, rheumatoid arthritis is still a diagnosis that ultimately has to be made with clinical judgment, said Ronald van Vollenhoven, MD, PhD, professor of medicine and chief of clinical therapy research in inflammatory diseases at the Karolinska University in Sweden. His remarks came…

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