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RA: When Should DMARDs Be Started?

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The updated guideline on the management of rheumatoid arthritis, released in June, contains some new, overarching points of emphasis and some notable differences from earlier guidelines. It underscores the role of methotrexate as a cornerstone therapy and emphasizes minimizing glucocorticoids, when possible. To learn more, read the full article from The Rheumatologist, June 2021: "The ACR Releases an Updated Treatment Guideline for Rheumatoid Arthritis."

In patients with moderate to high disease activity who have never previously taken a DMARD, a conditional recommendation is to start a conventional synthetic DMARD without short-term glucocorticoids.