Biopsy for Lupus Nephritis From the College | June 26, 2025 The ACR recently released a new guideline on the screening, treatment and overall management of lupus nephritis in children and adults. It specifically addresses when and how to use kidney biopsy in the diagnosis of lupus nephritis. These recommendations should not be used to limit or deny access to therapies because treatment decisions may vary due to the unique clinical situation and personal preferences of each individual patient. According to the guideline, prompt percutaneous kidney biopsy should be performed to: A. Confirm the diagnosis B. Rule out mimicking diseases C. Guide therapy decisions D. All of the above None Time's up