COVID-19 & Rheumatic Disease Flare From the College | May 8, 2025 The development of a vaccine for COVID-19 changed the course of the pandemic; however, it also raised questions about whether to withhold or reduce immunosuppressive therapies and other medications for patients with inflammatory, rheumatic and musculoskeletal disease. Read the full article. A recent study examining disease flares after COVID-19 vaccination found the following factors were associated with a higher chance of flare: A. Higher disease activity before vaccination B. Cessation or reduction of anti-rheumatic medications before vaccination C. The type of inflammatory, rheumatic and musculoskeletal disease D. A and B, but not C None Time's up
