Gout: What Urate-Lowering Therapy Should Be the First-Line Treatment? From the College | July 27, 2022 The 2020 ACR Guideline for the Management of Gout is intended to provide guidance for the management of patients with gout, and includes recommendations on the indications for and optimal use of urate-lowering therapy (ULT), treatment of gout flares, and lifestyle and other medication recommendations. Review our article for details: "Gout Management Recommendations from the ACR’s 2020 Guideline," or refer to the full guideline. In a patient with stage IV CKD with recurrent flares of gout and hyperuricemia, based on the 2020 ACR guideline, which is the preferred first-line urate-lowering therapy? A. Febuxostat B. Allopurinol C. Pegloticase D. Probenacid None Time's up
