When to Start Lupus Nephritis Therapy From the College | September 26, 2025 The ACR recently released a new guideline on the screening, treatment and overall management of lupus nephritis in children and adults. It includes recommendations regarding the initiation of therapy for patients with lupus nephritis. These recommendations should not be used to limit or deny access to therapies because treatment decisions may vary due to the unique clinical situation and personal preferences of each individual patient. Lupus nephritis therapy should be initiated: A. When lupus nephritis is suspected B. As soon as possible after diagnosis C. 6 months following the initial diagnosis of systemic lupus erythematosus if the patient has not responded to hydroxychloroquine D. In stages, starting with glucocorticoids and escalating to triple therapy within three months of diagnosis None Time's up
