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Search results for: fracture

Researchers Seek to Predict & Prevent Rheumatoid Arthritis

Jeffrey A. Sparks, MD, MMSc, & Kevin D. Deane, MD, PhD  |  June 21, 2018

Preventing adverse outcomes in individuals who have rheumatic diseases is a daily goal for rheumatologists. For example, rheumatologists prescribe medications and perform screening to prevent erosions in rheumatoid arthritis (RA), renal failure in systemic lupus erythematosus and flares across all diseases. Many of these actions are classified as secondary or tertiary prevention, because individuals have…

Filed under:Rheumatoid Arthritis Tagged with:lifestyleMetricsrisk assessmentRisk Factors

Hip Bone Deterioration May Differ Significantly Between Men & Women

Marilynn Larkin  |  June 12, 2018

NEW YORK (Reuters Health)—Various image analysis techniques show sex-specific patterns of bone deterioration at the hip, suggesting that men and women should be assessed differently for hip fracture risk, researchers say. “One major contribution of this work is the integration of data-driven computational anatomy approaches, which showed that proximal femur fragility linked to fracture seems…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:bone mineral density (BMD)Fractureship fracturehip fracture riskOsteoporosisSex Differences

FDA Approves Denosumab for Glucocorticoid-Induced Osteoporosis

Michele B. Kaufman, PharmD, BCGP  |  June 11, 2018

Denosumab is now approved to treat adults with glucocorticoid-induced osteoporosis…

Filed under:ConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:denosumabFDAGlucocorticoid-Induced OsteoporosisOsteoporosisosteoporosis treatmentsU.S. Food and Drug Administration (FDA)

Spine Surgery May not Be Needed to Ease Back Pain from Osteoporosis

Lisa Rapaport  |  June 3, 2018

(Reuters Health)—Patients with acute pain from osteoporosis damage to the spine don’t experience any more relief from surgery to inject cement into cracked or broken vertebrae than they would with a sham procedure, a recent trial in The Netherlands suggests. All of the patients in the experiment had compression fractures, which can happen when osteoporosis…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:Back painCristina FiranescuEvan DaviesOsteoporosisspine surgery

Alendronate May Provide Cardiovascular Benefits; Plus FDA Approves Subcutaneous Tocilizumab

Michele B. Kaufman, PharmD, BCGP  |  May 28, 2018

New research has linked alendronate to reduced cardiovascular death in hip fracture patients…

Filed under:Drug Updates Tagged with:alendronatecardiovascularFDAFractureship fractureJuvenile Arthritis (JIA)polyarticular juvenile idiopathic arthritistocilizumabU.S. Food and Drug Administration (FDA)

6 Things Endocrinologists Want Rheumatologists to Know

Vanessa Caceres  |  May 17, 2018

In your daily contact with rheumatology patients, you likely come across several who have type 1 or 2 diabetes. Are you doing all you can to maximize their treatment? Most physicians know about the damaging health effects of uncontrolled diabetes. From vision loss to kidney failure to nerve damage, those with diabetes require regular vigilance…

Filed under:Conditions Tagged with:collaborationcommunicationdiabetesinterdisciplinarySteroids

Case Review: MRI Leads to Non-Rheumatic Diagnosis Surprise

Anna Helena Jonsson, MD, PhD, & Julia F. Charles, MD, PhD  |  May 17, 2018

Rheumatologists often rely on magnetic resonance imaging (MRI) in the evaluation of suspected muscular diseases. Here, we describe a case in which unexpected findings on MRI pointed to a diagnosis rarely considered as a mimicker of rheumatologic disease. The Case A 19-year-old man of Middle Eastern descent was admitted to our hospital for evaluation of…

Filed under:Conditions Tagged with:anorexia nervosamagnetic resonance imagingMRI

Denosumab Is Effective for Glucocorticoid-Induced Osteoporosis

Lara C. Pullen, PhD  |  May 15, 2018

A study identified denosumab as a useful treatment for patients initiating or continuing glucocorticoids who are at risk for fractures. Denosumab had clinical effects similar to risedronate but was more effective than risedronate in the improvement of bone mineral density at the lumbar spine…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:bisphosphonatesdenosumabGlucocorticoid-Induced OsteoporosisOsteoporosisosteoporosis treatmentsrisedronate

Romosozumab Has Biggest BMD Benefit in First Year of Treatment

Anne Harding  |  May 14, 2018

NEW YORK (Reuters Health)—Romosozumab shows smaller benefits for increasing bone mineral density (BMD) in the second year of treatment compared to the first, new research suggests. The extension of a phase 2 study in postmenopausal women with low bone mass also found BMD decreased sharply when patients on romosozumab were switched to placebo after two…

Filed under:ConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:bone mineral density (BMD)humanized monoclonal antibodyOsteoporosisosteoporosis treatmentsphase 2 studypostmenopausal womenromosozumab

RA Patients May Not Receive Needed Osteoporosis Screening & Treatment

Arthritis Care & Research  |  May 4, 2018

New research examined the frequency of osteoporosis screening and treatment for RA patients from 2003–2014, including four years following the release of the 2010 ACR guideline on glucocorticoid-induced osteoporosis prevention and treatment. The results: Approximately half of RA patients for whom treatment was indicated never received osteoporosis medication. Researchers also found that RA patients, despite their increased risk for developing osteoporosis, were not more likely to receive osteoporosis care than OA patients…

Filed under:ConditionsOsteoarthritis and Bone DisordersResearch RheumRheumatoid Arthritis Tagged with:Arthritis Care & Researchfracture riskfracture risk factorsFracturesGlucocorticoid-Induced OsteoporosisGlucocorticoidsOsteoporosisRheumatoid Arthritis (RA)

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