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mRNA CAR T Cell Therapy Receives FDA’s Rare Pediatric Designation to Treat Juvenile Dermatomyositis

Michele B. Kaufman, PharmD, BCGP  |  January 30, 2025

FDA has granted Descartes-08, an mRNA chimeric antigen receptor T cell therapy, a rare pediatric disease designation for the treatment of juvenile dermatomyositis.

Filed under:Biologics/DMARDsConditionsDrug UpdatesMyositis Tagged with:chimeric antigen receptor T (CAR-T) cellsFDAjuvenile dermatomyositisU.S. Food and Drug Administration (FDA)

Reproductive Health, Biosimilars & More in Focus at SOTA 2025

Ruth Jessen Hickman, MD  |  January 30, 2025

Reproductive health, biosimilars, IgG4-related disease and much more—five speakers give us a sneak peek into important topics being addressed at the ACR’s 2025 State-of-the-Art Clinical Symposium, April 4–6.

Filed under:Biologics/DMARDsConditionsEducation & TrainingGuidanceMeeting ReportsOther ACR meetings Tagged with:ACR State-of-the-Art Clinical SymposiumBiosimilarsIgG4 related diseaseLupusOsteoporosispregnancypregnancy complicationspregnant womenskinState-of-the-Art Clinical Symposium

Precision Medicine on a Population Level: Can Digital Health Technology Improve Access to Rheumatologic Care?

Daniel H. Solomon, MD, MPH, & Andrew Concoff, MD, FACR  |  January 16, 2025

Over our 25 years as rheumatologists, care has advanced greatly. We each completed our rheumatology training in the late 1990s when both infliximab and etanercept first arrived on the U.S. market, ushering in the era of biologics in rheumatology. Since this time, our greater understanding of the immunologic basis of many rheumatic diseases has translated…

Filed under:ConditionsOpinionPractice SupportRheumatoid ArthritisSpeak Out RheumTechnology Tagged with:mPROscheduling app

Adobe Stock | Creativa Images

RA: How High Is the Toll?

Samantha C. Shapiro, MD  |  January 9, 2025

Patients with RA not only suffer from functional limitations, but also face increased healthcare costs, primarily due to prescription drug use, says Dr. Yinan Huang.

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:economic burdenMSPhDphysical burdenRA Resource CenterYinan Huang

ACR Image Competition 2024 Results, Part 2—People’s Choice

Ana Rita Fradique, MD  |  January 8, 2025

The 2024 Image Competition showcased images representing a diverse range of pediatric patients. Here, we showcase the images from Europe and Central Asia, which were selected by ACR Convergence 2024 attendees in the first plenary session to receive the People’s Choice Award. A Rare Presentation of a Rare Disease An 18-month-old boy from Angola was…

Filed under:ConditionsMyositis Tagged with:image case reportImage Competitionjuvenile dermatomyositisPediatric

New Committee Chair Wants to Connect ACR Members Through Education

Vanessa Caceres  |  January 7, 2025

As new chair of the Committee on Education, Marcy Bolster, MD, wants to foster opportunities for rheumatologists and other specialists to connect through education.

Filed under:Education & TrainingProfiles Tagged with:ACR Committee on EducationLeadershipVolunteer

FDA Approves Bimekizumab-bkzx (Bimzelx) for 3 New Rheumatic Indications

Michele B. Kaufman, PharmD, BCGP  |  December 30, 2024

The FDA has approved bimekizumab-bkzx for the treatment of adults with psoriatic arthritis, non-radiographic axial spondyloarthritis and ankylosing spondylitis.

Filed under:Axial SpondyloarthritisBiologics/DMARDsConditionsDrug UpdatesPsoriatic Arthritis Tagged with:Ankylosing Spondylitisbimekizumab-bkzxFDA approvalnon-radiographic axial spondyloarthritisnr-axSpAPsoriatic ArthritisU.S. Food and Drug Administration (FDA)

Black family, healthcare and a pediatrician talking to a patient in the hospital for medical child care. Kids, trust or medicine and a nurse consulting a boy with his mother in the clinic for health.

Youthful Exuberance: The Year in Review for Pediatric Rheumatology

Jason Liebowitz, MD, FACR  |  December 20, 2024

WASHINGTON, D.C.—It is no small task to summarize an entire year’s worth of research accomplishments in any field of medicine, let alone one as complex as rheumatology. At ACR Convergence 2024, the Pediatric Year in Review not only provided a thoughtful summary, but also grouped advances along several different themes. Immune Health & More Jessica…

Filed under:ACR ConvergenceConditionsGuidanceMeeting ReportsPediatric ConditionsResearch Rheum Tagged with:ACR Convergence 2024Pediatricsyear in review

Editor's Pick

Weathering the Cytokine Storm: Macrophage Activation Syndrome in Adults & Children

Katie Robinson  |  December 18, 2024

Peter Nigrovic, MD, provides a practical guide to the diagnosis & treatment of macrophage activation syndrome (MAS) in children & adults.

Filed under:ConditionsOther Rheumatic ConditionsPediatric Conditions Tagged with:Arthritis & RheumatologyEditor's PickImmunologymacrophage activation syndromeMAS

Retroperitoneal Fibrosis & IgG4-Related Disease

Mithu Maheswaranathan, MD  |  December 11, 2024

WASHINGTON, D.C.—Retroperitoneal fibrosis (RPF) is often a challenging diagnosis to make, given a lack of serologic biomarkers and often difficulty in accessing tissue for biopsy, especially in cases confined to the retroperitoneum. The topic of retroperitoneal fibrosis was discussed during the CARE to Test Your Knowledge: Retroperitoneal Fibrosis session at ACR Convergence 2024. John Stone,…

Filed under:ACR ConvergenceConditionsOther Rheumatic Conditions Tagged with:ACR Convergence 2024IgG4 related diseaseIgG4-RDretroperitoneal fibrosis

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