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New Test Yields Rapid Infliximab Drug Concentrations

Will Boggs, MD  |  December 22, 2016

NEW YORK (Reuters Health)—A new test provides rapid infliximab drug concentrations that enable immediate dosing adjustments, researchers from Belgium report. “With this rapid test, our biggest wish is to persuade physicians to now perform and use infliximab measurements also in their own daily clinical practice, as many practical and organizational issues that went along with…

Filed under:Biologics/DMARDsDrug Updates Tagged with:Biologicsdrug developmentinfliximab

Certolizumab Pegol Usage Compatible with Breastfeeding

Michele B. Kaufman, PharmD, BCGP  |  December 20, 2016

In a small-scale study, researchers found that no, or minimal amounts of, certolizumab pegol transfers from mothers taking the drug to nursing infants…

Filed under:Drug Updates Tagged with:breast milkbreastfeedingCertolizumab Pegolinfantspregnancy

The OPAL Beyond Study: Tofacitinib Phase 3 Results Positive for Treating PsA

Michele B. Kaufman, PharmD, BCGP  |  December 20, 2016

In a recent study, patients with psoriatic arthritis taking tofacitinib had a decrease in disease activity compared with placebo…

Filed under:ConditionsDrug UpdatesPsoriatic Arthritis Tagged with:Disease-modifying antirheumatic drugs (DMARDs)Janus Kinase InhibitorsPsoriatic ArthritisTofacitinib

The Future of Pediatric Rheumatology Grounded in Evolution of Childhood Arthritis and Rheumatology Research Alliance

Yukiko Kimura, MD, & Laura E. Schanberg, MD  |  December 15, 2016

Pediatric rheumatology was formally recognized as a specialty in 1991 by the American Board of Pediatrics. Prior to this time, children with rheumatic diseases were treated by a hodgepodge of providers. In addition to providers who had training as pediatric rheumatologists, general pediatricians, adult rheumatologists, allergist-immunologists, orthopedists, pediatric infectious disease specialists and others treated children…

Filed under:ConditionsPediatric ConditionsProfessional TopicsProfiles Tagged with:CARRAChildhood Arthritis & Rheumatology Research AlliancefutureHistorypatient carePediatricProfilerheumatology

Rheumatology Case Report: Systemic Capillary Leak Syndrome and Rheumatoid Arthritis

Alexis Smith, MD, & Angus Worthing, MD, FACP, FACR  |  December 15, 2016

Systemic capillary leak syndrome (SCLS) is a very rare disorder, characterized by recurrent episodes of severe hypotension, hypoalbuminemia and hemoconcentration.1 Attacks of SCLS occur in three phases: 1) prodrome; 2) hypovolemia with weight gain; and 3) hypervolemia with fluid overload and polyuria often complicated by pulmonary edema. Often, compartment syndrome can lead to rhabdomyolysis as…

Filed under:ConditionsRheumatoid Arthritis Tagged with:case reportconditionsoutcomepatient careRheumatoid arthritisrheumatologysystemic capillary leak syndromeTreatment

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Assessing Autoimmune Disease Symptoms in Silicone Breast Implant Recipients

Charles Radis, DO  |  December 15, 2016

My nurse, Joanne, took me aside before I began my next consult. “Room No. 5, breast implant patient. Her lawyer organized the records.” She handed me a hefty three-ring notebook organized by color-coded tabs. “Her attorney called just now,” Joanne raised an eyebrow, “and told me to tell you that, to save time, he highlighted…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:Autoimmune diseasebreast implantDiagnosisLupuspatient carephysicianrheumatologistsiliconeSLEsymptom

Infection Greater Worry Than Flare: Collaborative Guideline Offers Guidance to Prevent Joint Replacement Complications & Failure

Susan Bernstein  |  December 14, 2016

WASHINGTON, D.C.—Total joint arthroplasty is one of the most common surgical procedures performed on adults with end-stage arthritis. One recent estimate showed that 2.5 million individuals in the U.S. are living with a total hip replacement and 4.7 million are living with knee replacements. For their patients with inflammatory arthritis, rheumatologists and orthopedic surgeons must…

Filed under:Clinical Criteria/GuidelinesMeeting ReportsProfessional Topics Tagged with:2016 ACR/ARHP Annual Meetingdraft guidelineguideline projectjoint implant failurePerioperative Management of Anti-Rheumatic Medications in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Knee Arthroplastyperioperative periodpostoperative infection

MACRA: More Points, Smarter Future

Susan Bernstein  |  December 14, 2016

As the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA) is implemented in January with new models for quality-based reimbursement payments, rheumatologists must seize control of how they will be paid now—and in the future. This message was stressed by speakers during Holy MACRA! How to Survive and Thrive in the Era of MACRA,…

Filed under:Billing/CodingMeeting ReportsPractice SupportProfessional Topics Tagged with:2016 ACR/ARHP Annual MeetingAdvanced Alternative Payment MethodAPMMACRAMedicare Access and CHIP Reauthorization Act of 2015Merit-Based Incentive Payment SystemsMIPSRISE registry

Advocating Where It Counts: A Conversation with Incoming Government Affairs Committee Chair Angus Worthing, MD, FACR, FACP

Carina Stanton  |  December 14, 2016

As he prepares to take on his newest volunteer role with the ACR, leading the Government Affairs Committee (GAC), Angus Worthing, MD, FACR, FACP, is looking forward to making the most of the opportunities that a unified government can offer the ACR in advocating for rheumatology care. “Advocacy is an investment in our profession—regardless of…

Filed under:Legislation & AdvocacyProfessional TopicsProfiles Tagged with:ACR Government Affairs CommitteeAdvocacyAngus Worthing

GCA Relapse Possible When Discontinuing Tocilizumab

Michele B. Kaufman, PharmD, BCGP  |  December 14, 2016

A recent study found that although patients with giant cell arteritis respond positively to long-term tocilizumab treatment, relapse may occur after discontinuing the medication…

Filed under:Biologics/DMARDsDrug Updates Tagged with:GCAgiant cell arteritis (GCA)tocilizumab

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