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Search results for: interstitial lung disease

Updates in Juvenile Dermatomyositis: Pathogenesis & Patient Care

Jason Liebowitz, MD, FACR  |  July 17, 2021

Experts provided an update on juvenile dermatomyositis, discussing patient care, treatment options and the pathogenesis of disease.

Filed under:ConditionsMeeting Reports Tagged with:juvenile dermatomyositisPathogenesisPediatric RheumatologyPediatric Rheumatology SymposiumPRSYM

3 Educators Offer Lessons Learned on Rheumatology Training

Leslie Kahl, MD, Sheryl Mascarenhas, MD, & Rachel M. Wolfe, MD  |  July 15, 2021

Leslie Kahl, MD, on Coaching I have been an academic clinician-educator for my entire career and, like most of my colleagues, have been called upon to advise, mentor and coach countless trainees and junior faculty members. Unlike most clinician-educators, though, I also served as associate dean for student affairs at Washington University School of Medicine,…

Filed under:Education & Training Tagged with:FellowsFellows-in-Trainingfellowship program director

Rituximab Seems Safe & Effective for Systemic Sclerosis

Marilynn Larkin  |  June 22, 2021

NEW YORK (Reuters Health)—Rituximab seemed to be a safe and effective treatment for systemic sclerosis (SSc) in a placebo-controlled validation trial in Japan.1 “A number of studies have examined B-cell depletion therapy for systemic sclerosis, and many of them have suggested that [this] is effective in treating systemic sclerosis,” Ayumi Yoshizaki, MD, tells Reuters Health…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:rituximabsystemic sclerosis (SSc)

Case Report: Digital Ulcers & Weight Loss in a Pediatric Patient

Anusha Vuppala, MD, & Sarwat Umer, MD  |  June 13, 2021

Juvenile dermatomyositis (JDM) is a childhood form of inflammatory myopathy affecting children younger than 18 years. The diagnosis of JDM is based on characteristic clinical features of proximal muscle weakness, skin rash, elevated muscle enzymes, magnetic resonance imaging and muscle biopsy.1 Autoantibodies seen in patients with inflammatory myopathy are not only associated with particular phenotypes…

Filed under:ConditionsPediatric Conditions Tagged with:case reportinterstitial lung disease (ILD)juvenile dermatomyositisPediatric

Sarcoidosis in the Spotlight: Screening, Treatment & More Insights into Sarcoidosis

Jason Liebowitz, MD, FACR  |  June 1, 2021

An expert discussed the screening and treatment of sarcoidosis and drug-induced sarcoidosis-like reactions during the 2021 ACR State-of-the-Art Clinical Symposium.

Filed under:ConditionsMeeting Reports Tagged with:ACR State-of-the-Art Clinical SymposiumheartSarcoidosisVitamin D

Myositis Management: Clinical Trials Provide New Insights into Treatment Options

Jason Liebowitz, MD, FACR  |  May 24, 2021

Advancements in the treatment of myositis are on their way, according to Hector Chenoy, PhD, FRCP, who outlined the latest clinical trials during the 2021 ACR State-of-the-Art Clinical Symposium.

Filed under:ConditionsMeeting ReportsMyositis Tagged with:ACR State-of-the-Art Clinical Symposiumjakinibmyositis

A Mystery Case of Abdominal Masses

Vania Lin, MD, MPH, Robert Odrobina, MD, Maria A. Pletneva, MD, PhD, & Dorota Lebiedz-Odrobina, MD, RhMSUS  |  May 13, 2021

Common variable immuno­deficiency (CVID) is a common primary immuno­deficiency disease, with an estimated incidence of one per 25,000–50,000 individuals.1 The classic presen­tation includes frequent bacterial infections, secondary to dysfunctional B cell differ­entiation, impaired immunoglobulin production and diminished antibody response. The clinical presentation may be heterogenous and may include granulomatous disease as an uncommon manifestation. Granulo­matous…

Filed under:Conditions Tagged with:case reportCommon variable immunodeficiencyGranulomatosis

Clockwise from top: Image A shows the periungual ulceration (arrow) of the fifth digit, as well as the prior amputation of the second digit. Image B shows a longitudinal ultrasound of the palmar aspect of the ulnar right wrist. In the center of the image, the ulnar artery is in view and color Doppler flow is visualized within the vessel until there is a reversal of flow demonstrated by color change, followed by severe attenuation of flow distally. Distal to the cessation of flow, the vessel appears hypoechoic due to proliferation of the intima to the point of occluding the lumen. Image C shows a transverse view at the level of white line in Image B, with endothelial proliferation seen around a central lumen of the artery (a), next to the vein (v) and ulnar nerve (n). Image D, shows a transverse view at the level of the black line in Image B, where the arterial lumen (a) is occluded.

Insights Into Ulnar Artery Occlusion in Systemic Sclerosis

Devin M. Driscoll, MD, Andreea M. Bujor, MD, PhD, & Eugene Y. Kissin, MD, Rhmsus  |  April 17, 2021

A 51-year-old man with a history of limited systemic sclerosis with Raynaud’s phenomenon and pulmonary hypertension being treated with tadalafil and macitentan presented to a clinic with ulceration of his right pinkie. The patient had injured the finger two months earlier. He reported poor healing and the presence of a persistent ulcer since the injury….

Filed under:Conditions Tagged with:systemic sclerosis (SSc)Ultrasoundvascular disease

Case Report: Mycosis Fungoides in Dermatomyositis

Barrett Ford, MD, Chandana Shilpa Ravipati, DO, & Nirupa Patel, MD  |  March 15, 2021

Dermatomyositis (DM) is an idiopathic inflammatory myopathy involving proximal muscle weakness and skin rash. An associated increased risk of malignancy is well established.1 The most frequent malignancies are related to the ovary, endometrium, lung, gastrointestinal tract, prostate, breast and lymphatics.2 On rare occasions, DM has been reported with certain types of non-Hodgkin’s lymphoma, specifically cutaneous…

Filed under:ConditionsMyositis Tagged with:case reportdermatomyositis (DM)mycosis fungoides

ACR Convergence 2020

Interfering with Interferon: Experts Discuss IFN Signaling & IFN Inhibition Treatment Possibilities

Mary Beth Nierengarten  |  January 25, 2021

NIH investigators describe key features and genetic causes of Mendelian interferonopathies, & treatment approaches that may indicate the efficacy of IFN inhibition.

Filed under:ACR ConvergenceConditionsMeeting Reports Tagged with:ACR Convergence 2020interferonJAK inhibitorsjakinibsignaling

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