Can principles from engineering provide a broader understanding of how the human skeleton works and be used to help prevent a common and often consequential event for people as they age—bone fractures? Research from a team of investigators that includes orthopedic surgeons and mechanical engineers suggests that, yes, looking at how engineered materials, such as…
Studies explore role of STING pathway in bone remodeling, denosumab to reduce fracture risk, autotaxin’s role in fibrosis, SSc
Working both to support bone formation and suppress it, a new study reveals orexin neuropeptides are essential regulators of skeletal homeostasis
Current therapies target pathways of bone remodeling, but rheumatologists say a better understanding of the mechanisms of bone resorption, formation is needed to make an impact
Leptin inhibits serotonin synthesis in the neurons of the brainstem