Video: Every Case Tells a Story| Webinar: ACR/CHEST ILD Guidelines in Practice

An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

ANCA Mortality: Are Patients Doing Better?

  |  

The researchers also noted higher AAV mortality in non-Hispanic whites. “We hope that the mortality patterns presented here can be used to direct future research on the driving forces behind these trends,” conclude the authors. “Application of these data may help to decrease the nation’s AAV-related mortality.”

Lara C. Pullen, PhD, is a medical writer based in the Chicago area.

ADVERTISEMENT
SCROLL TO CONTINUE

References

  1. Fauci AS, Haynes BF, Katz P, et al. Wegener’s granulomatosis: Prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med. 1983 Jan;98(1):76–85.
  2. Tan JA, Dehghan N, Chen W, et al. Mortality in ANCA-associated vasculitis: Ameta-analysis of observational studies. Ann Rheum Dis. 2017 Sep;76(9):1566–1574.
  3. Wallace ZS, Lu N, Unizony S, et al. Improved survival in granulomatosis with polyangiitis: A general population-based study. Semin Arthritis Rheum. 2016 Feb;45(4):483–489.
  4. Steinberg AW, Wechsler ME, Fernández Pérez ER. Trends in antineutrophil cytoplasmic autoantibody-associated vasculitis-related mortality in the U.S., 1999 to 2017. Ann Intern Med. 2019 Oct 8. doi: 10.7326/M19-1564. [Epub ahead of print]

Related Articles
    Figure 2: Renal Biopsy

    The Classification & Diagnosis of Granulomatosis with Polyangiitis

    Based on the classification system developed by the Chapel Hill Consensus Conference, anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis is defined as a necrotizing vasculitis involving small vessels that is associated with myeloperoxidase (MPO) ANCA or proteinase 3 (PR3) ANCA and displays minimal immune deposits. The mechanism behind the pathogenesis of ANCA-associated vasculitis is not fully…

    Mortality from Anti-neutrophil Cytoplasmic Autoantibody-Associated Vasculitis Falling Slightly

    NEW YORK (Reuters Health)—Mortality rates in patients with antineutrophil cytoplasmic autoantibody-associated vasculitis (AAV) decreased from 1999 to 2017, according to records from the Centers for Disease Control and Prevention (CDC). “The mortality attributed to several rare diseases [e.g., hypersensitivity pneumonitis] has increased in recent years,” Alexander W. Steinberg, MD, from Saint Joseph Hospital, Denver, tells…

    Case Report: GPA Presenting as Neuropathy

    Granulomatosis with polyangiitis (GPA), is a type of anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) that affects small- to medium-sized vessels.1 It can occur equally in both men and women, with a reported mean age at onset of 55 years.2 The classical presentation of GPA includes upper respiratory tract (i.e., chronic sinusitis, serous otitis and…