Anti-TNF-Associated Skin Lesions Common in Inflammatory Bowel Disease

“We recommend close surveillance by the treating physician, explaining above all preventive measures for dry skin, before treatment is commenced and early referral to a dedicated dermatologist,” Dr. Cleynen concludes. “In our experience, this meant resolution of the skin problems in many patients, and only a low number of patients needing to stop anti-TNF treatment because of the skin problem.”

She adds, “An additional important note for the physicians is the appearance of alopecia areata/universalis with this class of drugs in a few patients, which can be severe and irreversible.”

The study was partly funded by Janssen Biologics. Dr. Cleynen and some of her co-authors report financial ties to the company.

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