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Anti-TNF Treatment Trial Encouraging for High-Risk APS Pregnancies

Thomas R. Collins  |  November 19, 2020

“Though it’s a small number, we are quite optimistic and looking forward to continuing the trial,” Dr. Salmon said. “Treatments to prevent poor pregnancy outcomes require an understanding of mechanisms of injury, and one needs animal studies and human observational studies to develop that understanding. But one can apply that understanding to test new treatments, and that’s—in fact—what we’re doing.”


Thomas Collins is a freelance medical writer based in Florida.

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References

  1. Buyon JP, Kim MY, Guerra MM, et al. Predictors  of pregnancy outcomes in patients with lupus: A cohort study. Ann Intern Med. 2015 Aug 4;163(3):153–163.
  2. Gelber SE, Brent E, Redecha P, et al. Prevention  of defective placentation and pregnancy loss by blocking innate immune pathways in a syngeneic model of placental insufficiency. J Immunol. 2015 Aug 1;195(3):1129–1138.
  3. Mehta B, Luo Y, Xu J, et al. Trends  in maternal and fetal outcomes among pregnant women with systemic lupus erythematosus in the United States: A cross-sectional analysis. Ann Intern Med. 2019 Aug 6;171(3):164–171.

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Filed under:ACR ConvergenceConditionsMeeting ReportsOther Rheumatic Conditions Tagged with:ACR Convergence 2020ACR Convergence 2020 - SLEAntiphospholipid Antibody Syndrome (APS)Hughes SyndromeLupus

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