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Is an Arthritis Vaccine Using Genetically Reprogrammed Stem Cells on the Horizon?

Elizabeth Hofheinz, MPH, MEd  |  Issue: August 2017  |  

These “designer” cells, says Dr. Guilak, point to a future vaccine. “With this research, we have laid the groundwork for a cell-based vaccine that can be used to treat a diverse array of autoimmune or inflammatory diseases. The sky is the limit.”

Elizabeth Hofheinz, MPH, MEd, is a freelance medical editor and writer based in the Greater New Orleans area.

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Contributors’ note: This work was supported by The Arthritis Foundation, the Nancy Taylor Foundation for Chronic Diseases, Shriners Hospitals for Children, the National Institutes of Health and the AO Foundation.

Reference

  1. Brunger JM, Zutshi A, Willard VP, et al. Genome engineering of stem cells for autonomously regulated, closed-loop delivery of biologic drugs challenges and opportunities. Stem Cell Reports. 2017 May 9;8(5):1202–1213.

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