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Complement Polymorphism Plays Role in RA Pathology

  |  Issue: June 2015  |  

In this way, the investigators revealed that a single amino acid change in C5 results in a complement polymorphism that is associated with a subtle change in individual component function that translates into dramatic effects on complement activity and RA disease risk. (posted 4/13/15)

Lara C. Pullen, PhD, is a medical writer based in the Chicago area.

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Reference
1. Giles JL, Choy E, van den Berg C, et al. Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis. J Immunol. 2015. Feb 27. doi: 10.4049/jimmunol.1402956 [Epub ahead of print].

 

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