What are the clinical implications for the updated classification criteria? They are a useful tool for rheumatology researchers because they reflect modern disease definitions and tests, said Richard Watts, honorary senior lecturer at Norwich Medical School at the University of East Anglia in the U.K. “These provisional criteria are clinically based, reflect current investigative practices and include ANCA, but they are not critically dependent on ANCA, nor on biopsy,” he said. “They provide a risk-based score rather than the old X-of-Y methodology, and have good specificity and sensitivity. They should be used for research purposes, but they will also improve the evidence base for decisions on therapy.”
Susan Bernstein is a freelance journalist based in Atlanta.
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