Video: Every Case Tells a Story| Webinar: ACR/CHEST ILD Guidelines in Practice

An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

  • Conditions
    • Axial Spondyloarthritis
    • Gout and Crystalline Arthritis
    • Myositis
    • Osteoarthritis and Bone Disorders
    • Pain Syndromes
    • Pediatric Conditions
    • Psoriatic Arthritis
    • Rheumatoid Arthritis
    • Sjögren’s Disease
    • Systemic Lupus Erythematosus
    • Systemic Sclerosis
    • Vasculitis
    • Other Rheumatic Conditions
  • FocusRheum
    • ANCA-Associated Vasculitis
    • Axial Spondyloarthritis
    • Gout
    • Psoriatic Arthritis
    • Rheumatoid Arthritis
    • Systemic Lupus Erythematosus
  • Guidance
    • Clinical Criteria/Guidelines
    • Ethics
    • Legal Updates
    • Legislation & Advocacy
    • Meeting Reports
      • ACR Convergence
      • Other ACR meetings
      • EULAR/Other
    • Research Rheum
  • Drug Updates
    • Analgesics
    • Biologics/DMARDs
  • Practice Support
    • Billing/Coding
    • EMRs
    • Facility
    • Insurance
    • QA/QI
    • Technology
    • Workforce
  • Opinion
    • Patient Perspective
    • Profiles
    • Rheuminations
      • Video
    • Speak Out Rheum
  • Career
    • ACR ExamRheum
    • Awards
    • Career Development
  • ACR
    • ACR Home
    • ACR Convergence
    • ACR Guidelines
    • Journals
      • ACR Open Rheumatology
      • Arthritis & Rheumatology
      • Arthritis Care & Research
    • From the College
    • Events/CME
    • President’s Perspective
  • Search

Immunology: What Is It Good For?

Bharat Kumar, MD, MME, FACP, FAAAAI, RhMSUS  |  Issue: November 2023  |  November 8, 2023

A More Meaningful Patient-Clinician Relationship

It is not just the cerebral element of immunology that aids us as rheumatologists. Knowledge of clinical immunology is very much an important aspect of being a practicing rheumatologist. When a patient asks a question, I feel like I should have a mastery of material to allow me to confidently answer their concerns. Patients are highly discerning and they are well aware of whether their clinicians know what they are talking about, or whether they are simply following an if-then algorithm in their mind.

During the earlier days of the pandemic, this was particularly critical with respect to vaccines. Many of my patients had very legitimate concerns about mRNA vaccines, a technology that was relatively novel to them. Rather than dismissing these concerns, I felt empowered by my knowledge of immunology to have detailed conversations about how vaccines impact their immune systems, especially those with complex disorders of immune dysfunction. Providing additional, expert information they otherwise could not obtain through generic advice from the internet and social media enabled them to make a more informed choice about vaccination.

ad goes here:advert-1
ADVERTISEMENT
SCROLL TO CONTINUE

Somewhat paradoxically, greater knowledge of immunology also enables us to speak to those with less knowledge of immunology. When we are better able to express the knowledge of immunology in more accurate metaphors and stories, we are better able to connect with our patients. The hegemonic view of autoimmunity being excess immune responses is simple, but is horribly inaccurate and, at times, confusing to patients. Don’t our patients deserve to get a more accurate view of what is causing their diseases? The only way we can answer that question is to delve deeper into the world of immunology.

A Bridge to Other Rheumatologists

It’s not only the patients who benefit from a rheumatologist who is knowledgeable of the immune system. So much of the nomenclature and terminology is based in immunology, down to the connotations of the seemingly random combinations of numbers. It’s one thing to know what interleukin 8, interferon-α, TGF-β, and CXCL8 are. It’s another to know that CXCL8 and IL-8 are actually the same thing. Without this degree of knowledge, the rheumatologist is dependent on another person to control the flow of information. Even with all the information available at our fingertips within smartphones, without the familiarity with, and instant access to this knowledge, we can be led astray in even casual conversations.

ad goes here:advert-2
ADVERTISEMENT
SCROLL TO CONTINUE

Page: 1 2 3 4 | Single Page
Share: 

Filed under:OpinionRheuminations Tagged with:Immunology

Related Articles

    Exploring the Complement System in Human Disease

    February 1, 2010

    Novel disease associations revealed by whole genome screens

    A 52-Year-Old Lupus Paper Remains Important Today

    December 14, 2020

    Over 50 years ago, an article appeared in The New England Journal of Medicine: “Immunologic Factors and Clinical Activity in Systemic Lupus Erythema­tosus.”1 Written by a young postdoctoral fellow, Peter H. Schur, MD, and colleagues, the article synthesized important work in the field at the time. What follows is a discussion of the historical context…

    Researchers Seek ANCA-Associated Vasculitis Subtype Markers

    October 19, 2020

    New research on complement activation in anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis underscores its important role in the patho­genesis of this disease, an autoimmune condition defined by inflammation of small- and medium-caliber blood vessels.1 ANCA testing is commonly performed to help diagnose granulomatosis with polyangiitis and microscopic polyangiitis, both of which are forms of ANCA-associated…

    2015 ACR/ARHP Annual Meeting: Cellular Triggers in Inflammatory Disease

    April 14, 2016

    SAN FRANCISCO—What factors help determine whether or not inflammation resolves, leading to healing, or becomes chronic, leading to disease and tissue destruction? A number of important cells, including toll-like receptors, mast cells, anti-citrullinated protein antibodies, complement and interferon, all play their own role in this process. By understanding how they act in innate and adaptive…

  • About Us
  • Meet the Editors
  • Issue Archives
  • Contribute
  • Advertise
  • Contact Us
  • Copyright © 2025 by John Wiley & Sons, Inc. All rights reserved, including rights for text and data mining and training of artificial technologies or similar technologies. ISSN 1931-3268 (print). ISSN 1931-3209 (online).
  • DEI Statement
  • Privacy Policy
  • Terms of Use
  • Cookie Preferences