Metabolic Profiling of SLE

The data also demonstrate that SLE patients have prevalent oxidative stress, as well as abnormal tryptophan metabolism through activity of aromatic amino acid decarboxylase or the kynurenine pathway. Taken together, the results suggest a path toward the development of a much needed diagnostic tool for SLE patients.

Lara C. Pullen, PhD, is a medical writer based in the Chicago area.

Reference

1. Bengtsson AA, Trygg J, Wuttge DM, et al. Metabolic profiling of systemic lupus erythematosus and comparison with primary Sjögren’s syndrome and systemic sclerosis. PLoS One. 2016 Jul 21;11(7):e0159384. eCollection 2016