Video: Every Case Tells a Story| Webinar: ACR/CHEST ILD Guidelines in Practice

An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

New Research into Rheumatoid Arthritis, Gout Includes Updates on Methotrexate, Biologics, Ultrasound

  |  Issue: September 2016  |  

A trial comparing the effects on pain of indomethacin to prednisolone found that they were equally effective, but prednisolone has fewer gastrointestinal side effects.10

“We are, at the moment, still in the phase where we don’t have a huge number of new drugs for the treatment of gout, so we are (compelled) to use our old drugs better.”

ADVERTISEMENT
SCROLL TO CONTINUE

Thomas R. Collins is a freelance medical writer based in Florida.

References

  1. Emery P, Bingham CO 3rd, Arendt C, et al. Certolizumab pegol in combination with dose-optimised methotrexate in DMARD-naive patients with early, active rheumatoid arthritis with poor prognostic factors: 1-year results from C-EARLY, a randomised, double-blind, placebo-controlled phase III study. Ann Rheum Dis. 2016 May 10 (Epub ahead of print)
  2. Genovese M, Kremer J, Zamani O, et al. Baricitinib in patients with refractory rheumatoid arthritis. N Engl J Med. 2016; 374:1243–1252.
  3. Dale J, Stirling A, Zhang R, et al. Targeting ultrasound remission in early rheumatoid arthritis: The results of the TaSER study, a randomised clinical trial. Ann Rheum Dis. 2016 Jun;75(6):1043–1050.
  4. Bayat S, Aati O, Rech J, et al. Development of a dual-energy computed tomography scoring system for measurement of urate deposition in gout. Arthritis Care Res (Hoboken). 2016 Jun;68(6):769–775.
  5. Zufferey P, Valcoy R, Fabreguet I, et al. A prospective evaluation of ultrasound as a diagnostic tool in acute microcrystalline arthritis. Arthritis Res Ther. 2015 Jul 22;17:188.
  6. Doherty M, Jansen TL, Nuki G, et al. Gout: Why is this curable disease so seldom cured? Ann Rheum Dis. 2012 Nov;71(11):1765–1770.
  7. Kuo CF, Grainge MJ, Mallen C, et al. Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study. Ann Rheum Dis. 2015 Apr;74(4):661–667.
  8. Becker MA, Fitz-Patrick D, Choi HK, et al. An open-label, 6-month study of allopurinol safety in gout: The LASSO study. Semin Arthritis Rheum. 2015 Oct;45(2):174–183.
  9. Wright DF, Duffull SB, Merriman TR, et al. Predicting allopurinol response in patients with gout. Br J Clin Pharmacol. 2016 Feb;81(2):277–289.
  10. Rainer TH, Cheng CH, Janssens HJ, et al. Oral prednisolone in the treatment of acute gout: A pragmatic, multicenter, double-blind, randomized trial. Ann Intern Med. 2016 Apr 5;164(7):464–471.

Related Articles