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An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

Psoriasis Tied to Higher Risk of Serious Liver Disease

Lisa Rapaport  |  

(Reuters Health)—People with chronic inflammatory disorders, such as psoriasis and rheumatoid arthritis (RA), may have an increased risk of developing serious liver damage, a recent study suggests. These inflammatory disorders are often treated with methotrexate, a medication linked to an increased risk of liver disease. For the current study, researchers followed more than 1 million…

Heated Gloves Provide Relief from Hand Pain, Dysfunction in Diffuse Systemic Sclerosis

Rosemarie A. Curley, MPT, DPT  |  

Raynaud’s phenomenon in scleroderma or systemic sclerosis (SSc) is associated with significant discomfort and functional disability, especially in the presence of digital ulcers.1 Having lived with diffuse systemic sclerosis (dSSc) for nearly a decade, I can attest to this. It has been my experience that the hand pain and dysfunction in dSSc stems from Raynaud’s…

Rheumatology Case Report: TINU Syndrome with Concomitant Synovitis

Ambreesh Chawla, MD, David Benderson, MD, Mikhail Kotlov, MD, Evan Leibowitz, MD, & Ashraf Raslan, MD  |  

Tubulointerstitial nephritis and uveitis (TINU) syndrome, also known as Dobrin syndrome, is a rare oculo-renal inflammatory disease. It was first described in 1975 by American physician Robert Dobrin, MD.1 It manifests as acute interstitial nephritis and bilateral uveitis. In addition, patients often experience nonspecific systemic findings, such as fever, weight loss, malaise, myalgia and arthralgia. TINU…

Rheumatologist’s Ping-Pong Prowess Sharpens His Skills with Patients

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Roughly 15 years ago, Steven K. Magid, MD, rheumatologist and chief medical information officer at the Hospital for Special Surgery (HSS) in N.Y., attended a social event for hospital employees. While chatting with other physicians, nurses, and lab techs, he watched one of his colleagues slaughter her opponents at Ping-Pong. “She was very skilled,” recalls Dr. Magid,…

Rheumatology Drug Updates: Efficacy Studied Following Accelerated Drug Approvals; Plus Secukinumab Meets Benchmark for Psoriasis

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Medications for serious or life-threatening conditions may receive accelerated approval from the U.S. Food and Drug Administration (FDA) by showing an effect on surrogate measures that are reasonably likely to predict a treatment’s clinical benefit. Post-approval confirmatory drug trials are then required to determine whether or not these effects translate into clinical improvements. In recent…

Hyperuricemia Doesn’t Always Indicate Gout in Rheumatic Disease

Veronika Sharp, MD, Alice Chuang, MD, Lily Kao, MD, RMSK, & Midori Jane Nishio, MD, RhMSUS  |  

A 57-year-old Ghanaian woman was referred to our rheumatology practice with acute, left elbow swelling and pain. The referring oncologist suspected gout, because the patient had hyperuricemia. Six months before, the patient was diagnosed with stage IV human T-lymphotropic virus type 1 (HTLV-1)-associated adult T cell lymphoma (ATLL). Her initial oncologic manifestations included multiple thoracic,…

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Research Targets Interferon Alpha in New Treatment Approach for CNS Lupus

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RETRACTED Editor’s note: The study this article reported on was retracted by the researchers. Key aspects could not be replicated, and they said, “Most importantly, the findings from behaviour studies and sequencing of microglia isolated from 564Igi autoimmune mice as shown in Figs. 1a, b, d and 3a, b are not substantiated upon further analysis…