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Lupus Nephritis Therapies Compared, Plus Naming Guidance for Biosimilars

Michele B. Kaufman, PharmD, BCGP  |  September 9, 2015

Comparing tacrolimus, mycophenolate mofetil and cyclophosphamide, tacrolimus was the most efficacious. Also, biosimilars may soon be easier to differentiate…

U.S. Doctors Group Says Planned Health Mergers Are Anti-Competitive

Reuters Staff  |  September 8, 2015

NEW YORK (Reuters)—Two proposed mergers of U.S. health insurers worth tens of billions of dollars would hurt competition in commercial health plans in as many as 17 states, the American Medical Association, the U.S. group that represents physicians, said on Tuesday. Aetna Inc. announced plans to buy smaller rival Humana Inc. in early July and…

Small Grants Fund Physical Activity to Combat OA

Richard Quinn  |  September 8, 2015

To increase access to community-based physical activity for arthritis patients, the Osteoarthritis Action Alliance has awarded funding to three programs designed to implement evidence-based physical activity programs and osteoarthritis education in their communities…

Can Childhood Fitness Predict Adult Knee Problems or OA?

Arthritis Care & Research  |  September 8, 2015

An Australian study found an association between child physical performance measures and adult knee structures. The data, collected from three points in participants’ lives, revealed a link between childhood activity and adult tibial cartilage volume and bone area.

Understanding SLE-Associated Skin Injury May Open the Door to Therapies

Lara C. Pullen, PhD  |  September 7, 2015

In a recent review, researchers addressed skin injury in patients with SLE, discussing the effects of ultraviolet rays on the skin and the subsequent generation of autoantibodies. They concluded that UV rays activate immune cells where IgG has been deposited, resulting in inflammation…

Arthritis May Be Worse in Poor Countries, but Seem Worse in Rich Ones

Janice Neumann  |  September 6, 2015

(Reuters Health)—A study of people with rheumatoid arthritis (RA) finds that those in wealthy nations are more troubled by it, even though people in poor countries have more severe symptoms. The results, tallied from 17 countries, suggest that cultural factors may influence patients’ perception of their illness, and possibly even the results of clinical trials…

Self-Monitoring of RA Treatment May Lead to Fewer Office Visits

Reuters Staff  |  September 5, 2015

NEW YORK (Reuters Health)—Self-monitoring of methotrexate therapy may curb healthcare utilization in rheumatoid arthritis (RA) and psoriatic arthritis, according to a new trial. The study indicates “that this novel model of care led to significant reductions in outpatient visits to the (clinical nurse specialist) and a reduction in visits to the GP, while maintaining the…

Growth Hormone Reduces Fractures in Women with Osteoporosis

Will Boggs, MD  |  September 4, 2015

NEW YORK (Reuters Health)—Growth hormone is associated with a decrease in fractures in women with postmenopausal osteoporosis even a decade after treatment ceases, researchers from Sweden report. “We were surprised and pleased to find that the patients had a reduced risk of fracture so many years after the growth hormone treatment was ceased,” Dr. Emily…

Use Behavioral ‘Nudging’ to Tackle Gender, Health Challenges

Joseph D'Urso  |  September 4, 2015

LONDON (Thomson Reuters Foundation)—Many of the world’s biggest challenges, such as encouraging people to buy life-saving drugs or unpicking deeply rooted sexism, can be tackled by using subtle psychological cues to change the way people behave, according to experts in London. Behavioral economics, also known as “nudging,” is about making people more likely to make…

Novartis Launches First U.S. Biosimilar Drug at 15% Discount

Ben Hirschler & Michael Shields  |  September 4, 2015

LONDON/ZURICH (Reuters)—Novartis kicked off a new era in U.S. medicine on Thursday with the launch of the first biosimilar copy of a biotechnology drug approved in the U.S., at a discount of 15% to the original. The Swiss drugmaker’s generics unit Sandoz said Zarxio, its form of Amgen’s white blood cell-boosting product Neupogen (filgrastim), would…

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