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An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

Research Across the Spectrum

Stephen I. Katz, MD, PhD  |  Issue: September 2009  |  

I have provided just a few examples of the NIAMS support of outstanding research in rheumatic diseases. These investments will help alleviate the suffering that these patients currently endure. At NIAMS, we are dedicated to the continued support of this basic and clinical research.

Dr. Katz is director of NIAMS at the NIH.

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References

  1. Meylan F, Davidson TS, Kahle E, et al. The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases. Immunity. 2008;29:79-89.
  2. Milner JD, Brenchley JM, Laurence A, et al. Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature. 2008;452:773-776.
  3. Charles N, Watford WT, Ramos HL, et al. Lyn kinase controls basophil GATA-3 transcription factor expression and induction of Th2 cell differentiation. Immunity. 2009;30:533-543.
  4. Aksentijevich I, Masters SL, Ferguson PJ, et al. An autoinflammatory disease with deficiency of the interleukin-1 receptor antagonist. N Engl J Med. 2009;360:2416-2427.
  5. The International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley JB, Alarcón-Riquelme ME, et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet. 2008;40:204-210.
  6. Hom G, Graham RR, Modrek B, et al. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med. 2008;358:900-909.
  7. Plenge RM, Seielstad M, Padyukov L, et al. TRAF-C5 as a risk locus for rheumatoid arthritis—a genomewide study. N Engl J Med. 2007; 357:1199-1209.
  8. Remmers EF, Plenge RM, Lee AT, et al. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med. 2007;357:977-986.

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