Video: Every Case Tells a Story| Webinar: ACR/CHEST ILD Guidelines in Practice

An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

  • Conditions
    • Axial Spondyloarthritis
    • Gout and Crystalline Arthritis
    • Myositis
    • Osteoarthritis and Bone Disorders
    • Pain Syndromes
    • Pediatric Conditions
    • Psoriatic Arthritis
    • Rheumatoid Arthritis
    • Sjögren’s Disease
    • Systemic Lupus Erythematosus
    • Systemic Sclerosis
    • Vasculitis
    • Other Rheumatic Conditions
  • FocusRheum
    • ANCA-Associated Vasculitis
    • Axial Spondyloarthritis
    • Gout
    • Psoriatic Arthritis
    • Rheumatoid Arthritis
    • Systemic Lupus Erythematosus
  • Guidance
    • Clinical Criteria/Guidelines
    • Ethics
    • Legal Updates
    • Legislation & Advocacy
    • Meeting Reports
      • ACR Convergence
      • Other ACR meetings
      • EULAR/Other
    • Research Rheum
  • Drug Updates
    • Analgesics
    • Biologics/DMARDs
  • Practice Support
    • Billing/Coding
    • EMRs
    • Facility
    • Insurance
    • QA/QI
    • Technology
    • Workforce
  • Opinion
    • Patient Perspective
    • Profiles
    • Rheuminations
      • Video
    • Speak Out Rheum
  • Career
    • ACR ExamRheum
    • Awards
    • Career Development
  • ACR
    • ACR Home
    • ACR Convergence
    • ACR Guidelines
    • Journals
      • ACR Open Rheumatology
      • Arthritis & Rheumatology
      • Arthritis Care & Research
    • From the College
    • Events/CME
    • President’s Perspective
  • Search

Rheum with a View

Richard S. Panush, MD  |  Issue: April 2011  |  April 13, 2011

Dr. Panush
Dr. Panush

A Musical Interlude

There was a piece in the literature recently about the illness of the musician Frederic Chopin.1 A favorite interest of mine has been rheumatology (and medicine) in history, literature, art, music, and biblical lore. I find it fascinating to try and understand how illness affected great artists, leaders, and history. Some examples include:

  • Saturnine gout causing the fall of the Roman Empire;
  • Sir William Pitt the elder’s gout forcing him to miss the parliamentary debate that enacted the tea tax and led to the colonies’ rebellion and the American revolution;
  • Tsaravich Alexis’ hemophiliac arthropathy precipitating Tsarina Alexandra’s invitation to Rasputin to help (mis)govern and the resultant fall of Imperial Russia leading to nearly a century of communist rule;
  • King George III’s porphyria and its subsequent implications for the colonies and Irish rule;
  • Napoleon’s loss of the fateful battle of Waterloo because of a hemorrhoid;
  • Renoir’s magnificent creations despite his crippling rheumatoid arthritis (RA);
  • The evident effect of his scleroderma on Klee’s painting; and
  • The historical and religious consequences of King Saul’s pituitary tumor (some references can be found in Panush and Caldwell; for others, ask me).2

I enjoyed reading about Chopin’s illness. The authors note Chopin’s hallucinations and speculate that his neurologic problems included temporal lobe seizures. I must briefly digress to my piano lessons and then return to Chopin. I took piano lessons beginning at about age seven; my parents wouldn’t let me quit until five years later. I hated it at the time. I desperately wanted to be outside playing baseball, basketball, or football with my friends rather than stuck in the house, compelled to take the after-school instruction and then practice as well. My most notable musical accomplishment was, at a prominent recital, to play my entire piece perfectly but an octave too low (for anyone who doesn’t know music, that’s probably equivalent to injecting the wrong joint or operating on the wrong limb). My younger sister was very good, however, and she got to play some terrific music, including Chopin’s polonaise #40 (Military, in A major). That moved me. I thought it was great music; it was played on Polskie Radio during the German invasion of Poland in 1939 to rally and inspire the Polish people (it failed).

ad goes here:advert-1
ADVERTISEMENT
SCROLL TO CONTINUE

Of course, now that I am older, I wish I learned piano better and retained some skill. I occasionally sit down and enjoy playing Massenet’s aragonaise or Mozart’s rondo. I have the music for the polonaise, but it not only eludes my meager skill, it also causes arthritis in my hands from the difficulty of the music.

Frederic Chopin
Frederic Chopin

Chopin’s use of piano to express his thoughts and feelings was virtuosic. He died at age 39 years of a chronic illness. His symptoms included cough, breathlessness, hemoptysis, constitutional symptoms (e.g., fatigue, “failure to thrive”), gastrointestinal symptoms including hematemesis, neurologic symptoms, and arthritis. What’s the diagnosis? Most of us would think of the possibility of one of the systemic rheumatic diseases. The literature indeed includes consideration of Churg-Strauss syndrome, but other of our disorders are conceivable.3 Note, however, that his father had respiratory disease, and his sister died young with similar symptoms. Other diagnostic possibilities include emphysema, bronchiectasis, tuberculosis, alpha-1- antitrypsin deficiency, hypo- or dys-gammaglobulinemia, allergic broncho-pulmonary aspergillosis, cystic fibrosis, and mitral stenosis. We don’t know what Chopin had, of course, and never will with certainty, so no diagnostic suggestion can be disputed. But isn’t Frederic Chopin a tribute to the human spirit, to the ability to triumph over adversity (which certainly not all our patients with chronic diseases can do)? We can only admire with awe the wonderful contributions he left us, despite illness, throughout his short life.

ad goes here:advert-2
ADVERTISEMENT
SCROLL TO CONTINUE

Orchestral Harmony, the Immune System, and Rheumatic Disease

When I was very young, we were just learning about the elegant complexity of the immune system, its dysfunction, and how that was important in rheumatic diseases. I recall someone describing its normally balanced intricacies as like orchestral harmony with the T cell as the conductor. One of my colleagues then, Selden Longley at the University of Florida, developed a very imaginative analogy of the immune system to football, with offensive and defensive coordinators, a coach, offensive and defensive players, quarterbacks, substitutes, and reserves that he used for his lectures to students. I’m no longer sure who conducts the immune symphony, but the players must still make music properly.

We don’t know what Chopin had, of course, and never will with certainty, so no diagnostic suggestion can be disputed. But isn’t Frederic Chopin a tribute to the human spirit?

I’m unabashedly delighted to be part of rheumatology at the University of Southern California. I think we have a division of which the football team could be proud. I’m therefore pleased today to include work by one of my new colleagues, Song Guo Zheng, a physician and an associate professor doing important research in our division, in collaboration with David Horwitz, our former division chief, and Zhongmin Liu, an immunologist at Tongji University in China, and others.4

Page: 1 2 3 | Single Page
Share: 

Filed under:ProfilesResearch Rheum Tagged with:Clinical researchImmune SystemLiterature

Related Articles

    Music May Help Reduce Pain

    November 5, 2016

    (Reuters Health)—As a complement to traditional pain relief tools, such as medication, listening to music may lessen acute or chronic pain related to cancer and other conditions, according to a new review. “We have seen and observed this effect in multiple clinical settings, such as medical hospitals and hospice-care facilities,” says author Dr. Jin Hyung…

    When Rheumatic Disease May Have Affected the Course of Western Civilization

    November 8, 2022

    The study of rheumatology (and medicine) in art, history, literature and music is engaging and informative.1-12 In this article, we present some instances when rheumatic and autoimmune diseases in certain individuals may have affected the course of history in Western civilization. ad goes here:advert-1ADVERTISEMENTSCROLL TO CONTINUEPhysicians are usually concerned, appropriately, with the effects of illness…

    Rheumatologist’s Musical Career Thrives Despite Medical Condition

    November 1, 2014

    Dr. Allen Steere nurtures passion for playing piano despite focal dystonia diagnosis

    Rheum with a View

    November 1, 2011

    Why I sometimes read poetry instead of medicine—and why you should, too

  • About Us
  • Meet the Editors
  • Issue Archives
  • Contribute
  • Advertise
  • Contact Us
  • Copyright © 2025 by John Wiley & Sons, Inc. All rights reserved, including rights for text and data mining and training of artificial technologies or similar technologies. ISSN 1931-3268 (print). ISSN 1931-3209 (online).
  • DEI Statement
  • Privacy Policy
  • Terms of Use
  • Cookie Preferences