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Seq & Ye Shall Find

Philip Seo, MD, MHS  |  Issue: January 2020  |  January 16, 2020


Dr. SeoPhilip Seo, MD, MHS, is an associate professor of medicine at the Johns Hopkins University School of Medicine, Baltimore. He directs the Johns Hopkins Vasculitis Center and the Johns Hopkins Rheumatology Fellowship Program.

References

  1. Sharp GC, Irvin WS, Tan EM, et al. Mixed connective tissue disease—an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med. 1972 Feb;52(2):148–159.
  2. Falk RJ, Jennette JC. Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med. 1988 Jun 23;318(25):1651–1657.
  3. Mammen AL, Chung T, Christopher-Stine L, et al. Autoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathy. Arthritis Rheum. 2011 Mar;63(3):713–721.
  4. Ponomarenko EA, Poverennaya EV, Ilgisonis EV, et al. The size of the human proteome: The width and depth. Int J Anal Chem. 2016;2016:7436849.
  5. Bazan J, Calkosinski I, Gamian A. Phage display—a powerful technique for immunotherapy: 1. Introduction and potential of therapeutic applications. Hum Vaccin Immunother. 2012 Dec 1;8:1817–1828.
  6. Larman HB, Zhao Z, Laserson U, et al. Autoantigen discovery with a synthetic human peptidome. Nat Biotechnol. 2011 May 22;29(6):535–541.
  7. Transcriptome fact sheet. National Human Genome Research Institute.
  8. Inglese J, Johnson RL, Simeonov A, et al. High-throughput screening assays for the identification of chemical probes. Nature Chem Biol. 2007 Aug;3(8):466–479.
  9. Macosko EZ, Basu A, Satija R, et al. Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets. Cell. 2015 May 21;161(5):1202–1214.
  10. Accelerating Medicines Partnership (AMP). National Institutes of Health.

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