Although used in the treatment of inflammatory neuropathies, such as Guillain-Barre syndrome, the efficacy of intravenous immunoglobulin (IVIG) in the treatment of Sjögren’s-related neuropathy is less apparent. Dr. Bhattacharyya does not typically use this therapy.
Sjögren’s syndrome remains a challenging disease to accurately diagnose and treat. The insights provided by Dr. McCoy and Dr. Bhattacharyya will help guide clinicians. Whether one sees the future as a glass half empty or half full, one thing is clear: Sicca symptoms, with and without accompanying neuropathy, require a broad differential, and the thoughtful physician is the one best prepared to help these patients in their care.
Jason Liebowitz, MD, completed his fellowship in rheumatology at Johns Hopkins University, Baltimore, where he also earned his MD. He is currently in practice with Arthritis, Rheumatic, & Back Disease Associates, New Jersey.
References
- Fauchais AL, Magy L, Vidal E. Central and peripheral neurological complications of primary Sjögren’s syndrome. Presse Med. 2012 Sep;41(9 Pt 2):e485–e493.
- Baer AN, Walitt B. Update on Sjögren syndrome and other causes of sicca in older adults. Rheum Dis Clin North Am. 2018 Aug;44(3):419–436.
- Anish L, Nagappa M, Mahadevan A, Taly AB. Neuropathy in elderly: Lessons learnt from nerve biopsy. Age Ageing. 2015 Mar;44(2):312–317.
