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Stop the Rheumatoid Arthritis (RA) Cascade Early

Sue Pondrom  |  Issue: May 2008  |  May 1, 2008

Whatever the future may hold for diagnosis and treatment, EACs have been instrumental, especially over the past 20 years, in providing better outcomes for rheumatoid arthritis patients. Patient studies have provided data to investigate RA from inception to later stages, resulting in valuable information leading to improved treatment for early RA patients.

Sue Pondrom is a medical journalist based in San Diego.

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References

  1. Raza K, Breese M, Nightingale P, et al. Predictive value of antibodies to cyclic citrullinated peptide in patients with very early inflammatory arthritis. J Rheumatol. 2005;32(2):231-238.
  2. Raza K, Falciani F, Curnow SJ, et al. Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin. Arthritis Res Ther. 2005;7:R784-R795.
  3. Quinn MA, Emery P. Are early arthritis clinics necessary? Best Pract Res Clin Rheumatol. 2005;19(1):1-17.
  4. Emery P, Breedveld FC, Dougados M, Kalden JR, Schiff MH, Smolen JS. Early referral recommendation for newly diagnosed rheumatoid arthritis: eEidence based development of a clinical guide. Ann Rheum Dis. 2002;61(4):290-297.
  5. Aletaha D, Ward MM, Machold KP, et al. Remission and active disease in rheumatoid arthritis: Defining criteria for disease activity states. Arthritis Rheum. 2005;52:2625-2636.
  6. Van Der Kooij SM, Van Der Bijl AE, Allaart CF, et al. Remission induction in early rheumatoid arthritis (RA) with initial infliximab and methotrexate therapy: The disease course after IFX discontinuation in the best trial. ACR Annual Scientific Meeting 2006; presentation 658.
  7. Wessels JA, van der Kooij SM, le Cessie S, et al. A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis. Arthritis Rheum. 2007;56(6):1765-1775.
  8. Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Allaart CF, et al. Comparison of treatment strategies in early rheumatoid arthritis. Ann Intern Med. 2007;146:406-415.

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Filed under:ConditionsRheumatoid Arthritis Tagged with:clinicDiagnosisDiagnostic CriteriaoutcomeRheumatoid Arthritis (RA)Treatment

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