The authors found that a mindset of “NSAID users can choose their own dose” irrespective of dosing recommendations and poor knowledge of maximum one-time and 24-hour dosing was associated with exceeding the daily dosing limit. The approach of starting with the lowest effective dose was inversely associated with exceeding the daily dosing limit. Additionally, these characteristics are potentially modifiable.
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One major limitation was the study’s low participation rate.
Michele B. Kaufman, PharmD, BCGP, is a freelance medical writer based in New York City and a pharmacist at New York Presbyterian Lower Manhattan Hospital.
- Kaufman DW, Kelly JP, Battista DR, et al. Exceeding the daily dosing limit of nonsteroidal anti-inflammatory drugs among ibuprofen users. Pharmacoepidemiol Drug Saf. 2018 Mar;27(3):322–331. doi: 10.1002/pds.439