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What We Know about COVID-19 in 2023: Variants, Vaccines, New Therapies & More

Ruth Jessen Hickman, MD  |  March 16, 2023

Although the virus is still a risk that needs to be managed, it’s encouraging to see less severe outcomes overall compared with the earliest days of the pandemic. “Having more people with impactful functional immunity to any infectious disease is important, whether we call that herd immunity or not,” says Dr. Kim. “But at least in our system right now, the majority of our hospitalizations are still for patients with COVID.”

Ruth Jessen Hickman, MD, is a graduate of the Indiana University School of Medicine. She is a freelance medical and science writer living in Bloomington, Ind.

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References

  1. Kim AHJ, Sparks JA. Immunosuppression and SARS-CoV-2 breakthrough infections. Lancet Rheumatol. 2022 Jun;4(6):e379–e380.
  2. COVID-19 vaccine clinical guidance summary for patients with rheumatic and musculoskeletal diseases. ACR. Version 5. Revised 2022 August 12.
  3. Mikuls TR, Johnson SR, Fraenkel L, et al. American College of Rheumatology guidance for the management of rheumatic disease in adult patients during the COVID-19 pandemic: Version 3. Arthritis Rheumatol. 2021 Feb;73(2):e1–e12.
  4. Centers for Disease Control and Prevention. Summary of variant surveillance. COVID data tracker. https://covid.cdc.gov/covid-data-tracker/#variant-summary. Accessed 2023 Jan 31.
  5. Callaway E. Coronavirus variant XBB.1.5 rises in the United States – is it a global threat?. Nature. 2023 Jan;613(7943):222–223.
  6. Hill L, Artiga S. COVID-19 cases and deaths by race/ethnicity: Current data and changes Over Time. Kaiser Family Foundation. 2022 Aug 22.
  7. Willis DE, Montgomery BEE, Selig JP, et al. COVID-19 vaccine hesitancy and racial discrimination among US adults. Prev Med Rep. 2022 Nov 28;31:102074.
  8. Hildreth JEK, Alcendor DJ. Targeting COVID-19 vaccine hesitancy in minority populations in the US: Implications for herd immunity. Vaccines (Basel). 2021 May 11;9(5):489.
  9. Kriss JL, Hung MC, Srivastav A, et al. COVID-19 vaccination coverage, by race and ethnicity – national immunization survey adult COVID module, United States, December 2020-November 2021. MMWR Morb Mortal Wkly Rep. 2022 Jun 10;71(23):757–763.
  10. Centers for Disease Control and Prevention. COVID data tracker weekly review. Accessed 2023 Jan 20.
  11. AstraZeneca. First participant dosed in SUPERNOVA PHASE I/III trial evaluating AZD5156, a next-generation long-acting antibody combination, for prevention of COVID-19. 2022 December 21.

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Filed under:Conditions Tagged with:COVID-19SARS-CoV-2

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