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What’s New in Psoriatic Arthritis?

David Pisetsky, MD, PhD  |  Issue: December 2025  |  October 28, 2025

As reported by Martin and colleagues, the study team performed Achilles elastography (EL-AQ) in 57 PsA patients with or without Achilles tendon involvement using ultrasound before and after controlled exercise (20 minutes on a stationary bicycle at medium resistance). As a measure of tendon properties, the MASEI (Madrid Sonographic Enthesis Score) was calculated.

The results showed the EL-AQ can discriminate between patients and controls and that changes can occur with or without clinical Achilles tendon involvement.

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These are interesting findings that extend the usual use of ultrasonography to assess changes in the mechanical properties of tendons; future studies will be needed to determine the extent to which these changes reflect inflammation and, therefore, may be modified by therapy.


David S. Pisetsky, MD, PhD, is a professor of medicine and integrative immunobiology at Duke University School of Medicine, Durham, N.C., and a staff rheumatologist at the Durham VA Medical Center. He also served as the first physician editor of The Rheumatologist.

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References

  1. Orbai A, Wang H, Grecu M, et al. Anti-peptidylarginine deiminase-2 (anti-PAD2) autoantibodies in psoriatic arthritis [abstract 0529]. Arthritis Rheumatol. 2025;77(suppl 9).
  2. Tskitishvili R, Hussein A, Tskhakaia I, et al. Risk of inflammatory bowel disease in psoriatic arthritis patients treated with IL-17 inhibitors [abstract 1183]. Arthritis Rheumatol. 2025;77(suppl 9).
  3. Mehta P, Yang M, Carrizo Abarza V, et al. Understanding the impact of overweight and obesity on treatment response in psoriatic arthritis: Results from a longitudinal cohort study [abstract 2691]. Arthritis Rheumatol. 2025;7(suppl 9).
  4. Tsibadze N, Tskhakaia I, Tan I. Mortality and major adverse cardiac events (MACE) with GLP-1 receptor agonists in psoriatic arthritis [abstract 0849]. Arthritis Rheumatol. 2025;7(suppl 9).
  5. Ritchlin C, Rangel-Moreno J, Rangel-Garcia A, et al. Axial psoriatic arthritis is phenocopied in a humanized mouse model [abstract 1753]. Arthritis Rheumatol. 2025;7(suppl 9).
  6. Raimondo M, Mohammadian H, Angeli M, et al. Skin-to-joint immune cell migration and synovial reprogramming in psoriatic arthritis onset [abstract 1757]. Arthritis Rheumatol. 2025;7(suppl 9).
  7. Vladimirova N, Hadsbjerg A, Krabbe S, et al. Unveiling sacroiliac joint involvement in psoriatic arthritis: MRI, radiographic, and clinical insights from 581 European routine care patients [abstract 0543]. Arthritis Rheumatol. 2025;7(suppl 9).
  8. Almansouri A, Li J, Alhadri A, et al. The incidence rate and risk factors of arrhythmias in patients with psoriatic arthritis [abstract 0522]. Arthritis Rheumatol. 2025;7(suppl 9).
  9. Wiebe E, Huscher D, Boyadzhieva Z, et al. Impact of Janus Kinase inhibitors on bone mineral density and microarchitecture in rheumatoid and psoriatic arthritis: Insights from a real-world cohort [abstract 0343]. Arthritis Rheumatol. 2025;7(suppl 9).
  10. Mikolajczak L, Kuhn H, Harrold L, Reed G. Impact of psoriatic arthritis disease activity and fatigue on subjective cognitive decline (‘brainfog’) [abstract 1421]. Arthritis Rheumatol. 2025;7(suppl 9).
  11. Eder L, Li X, Koppikar S, et al. The perimenopause period is associated with increased levels of disease activity in psoriatic arthritis [abstract  1714]. Arthritis Rheumatol. 2025;77(suppl 9).
  12. Martin Martin I, San Jose Mendez C, Jimenez Barrios S, et al. Role of achilles elastography in differentiating patients with early psoriatic arthritis [abstract 0107]. Arthritis Rheumatol. 2025;7(suppl 9).

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Filed under:ACR ConvergenceConditionsMeeting ReportsPsoriatic Arthritis Tagged with:ACR Convergence 2025ACR Convergence 2025 - PsAAxial Psoriatic Arthritis (axPsA)inflammatory bowel disease (IBD)Obesity

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