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Lara C. Pullen, PhD

Lara C. Pullen, PhD, is a medical writer with a PhD in microbiology/immunology from Northwestern University’s Feinberg School of Medicine. As a medical writer she has covered topics as diverse as diabetes, cardiovascular disease, and autism. Her favorite subject, however, is the role of the immune system in health and disease. Dr. Pullen is also the mother of three children, the youngest of whom has Prader-Willi Syndrome (PWS). She is an active member of the PWS community and a thought leader on the importance of the ketogenic diet for this patient population.

Articles by Lara C. Pullen, PhD

Living Well with Scleroderma

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—Can non-drug interventions improve the lives of patients with scleroderma? Janet L. Poole, PhD, OTR/L, professor and director of the Occupational Therapy Graduate Program of the School of Medicine, University of New Mexico, Albuquerque, addressed this question when she presented the ARHP Distinguished Lecture at the 2018 ACR/ARHP Annual Meeting. She discussed the challenges faced…

Destructive Arthritis: From Prevention to Progression to Remission

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—Josef S. Smolen, MD, professor of internal medicine and chair of the Department of Rheumatology, Vienna General Hospital, Austria, presented the prestigious Paul Klemperer, MD, Memorial Lecture at the 2018 ACR/ARHP Annual Meeting. Dr. Smolen, whose work is frequently cited, created the treat-to-target strategy for rheumatoid arthritis (RA). Dr. Smolen began by noting a simple…

Research Shows Genetic Links in ANCA-Associated Vasculitis

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—Ken Smith, MD, PhD, professor of medicine at the University of Cambridge, England, gave an update on anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) at the 2018 ACR/ARHP Annual Meeting. Although vasculitis tends to be defined first by vessel size, the clinical differentiation between the forms is not reliable, explained Dr. Smith. For example, granulomatosis with…

The Latest on Epigenetics in Immune-Mediated Disease

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—Because the epigenome has been implicated in a variety of rheumatic conditions, a Basic Research Conference was convened on Epigenetics in Immune-Mediated Disease in conjunction with the 2018 ACR/ARHP Annual Meeting. Melanie Ehrlich, PhD, professor of human genetics and genomics at Tulane University School of Medicine, New Orleans, opened the conference. She has a long…

State-of-the-Art Approaches to Rheumatic Disease Diagnosis, Management & Treatment

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—Held during the 2018 ACR/ARHP Annual Meeting, the ACR Review Course covered a wide range of topics for rheumatologists—from advances in pain and rheumatic disease management to the intersection of rheumatology and neurology. Session speakers shared insights, as well as state-of-the-art approaches to diagnosis, management and treatment. Inflammatory Myopathies Julie J. Paik, MD, MHS, assistant…

A Case Study in Sweet’s Syndrome with Pulmonary Involvement

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—Physicians from the University of Chicago presented an intriguing case of Sweet’s syndrome for the Clinical Pathological Conference during the 2018 ACR/ARHP Annual Meeting. Pankti Reid, MD, MPH, a rheumatology fellow at the University of Chicago, introduced the case of a white man who, in 2017, came under the care of the University of Chicago….

Draft Guidelines & Recommendations for Juvenile Idiopathic Arthritis

Lara C. Pullen, PhD  |  March 19, 2019

CHICAGO—The treatment of patients with juvenile idiopathic arthritis (JIA) is historically directed by clinical subtype. During a session at the 2018 ACR/ARHP Annual Meeting, speakers addressed the biological classification and treatment of JIA, discussing draft guidelines and recommendations, the impact of computer modeling on identifying JIA subtypes and subgroups of chronic arthritis. Guidelines & Recommendations…

IgG from Patients with Autoimmune Disease Activates Neutrophils

Lara C. Pullen, PhD  |  March 18, 2019

A recent study examined the effects of immunoglobulin G (IgG) on isolated neutrophils of patients with autoimmune disease. Researchers found different autoimmune diseases have distinct patterns of IgG-mediated integrin activation and neutrophil function, which may explain disease-specific differences in vascular damage and dysfunction…

Metabolic Profiling of SLE

Lara C. Pullen, PhD  |  March 12, 2019

Research examining the metabolic profile of SLE found increased oxidative activity, as well as lower levels of tyrosine and tryptophan, in SLE patients relative to controls, suggesting increased activity of aromatic amino acid decarboxylase. The results suggest metabolomics may have the ability to measure disease severity in SLE…

GI Disease in Early Systemic Sclerosis Associated with Worse Outcomes

Lara C. Pullen, PhD  |  March 5, 2019

In patients with systemic sclerosis (SSc), gastrointestinal disease may be associated with lower quality of life and increased risk of death. Research showed that SSc patients with severe GI disease had markers of muscle inflammation, skin fibrosis and vasculopathy…

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