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Lara C. Pullen, PhD

Lara C. Pullen, PhD, is a medical writer with a PhD in microbiology/immunology from Northwestern University’s Feinberg School of Medicine. As a medical writer she has covered topics as diverse as diabetes, cardiovascular disease, and autism. Her favorite subject, however, is the role of the immune system in health and disease. Dr. Pullen is also the mother of three children, the youngest of whom has Prader-Willi Syndrome (PWS). She is an active member of the PWS community and a thought leader on the importance of the ketogenic diet for this patient population.

Articles by Lara C. Pullen, PhD

New Data May Explain the Role of Sclerostin in Bone Formation

Lara C. Pullen, PhD  |  October 9, 2017

New research in mice shows that sclerostin deficiency may play a significant role in bone formation, possibly despite skeletal age. In the study, sclerostin-deficient mice more readily formed cortical bone and had increases in periosteal bone formation rates, as well as increased expression of the Wnt inhibitor Dkk1, than controls…

Adalimumab + Methotrexate Effective for Uveitis in JIA

Lara C. Pullen, PhD  |  October 2, 2017

Research has found that taking adalimumab plus methotrexate is effective for patients with juvenile idiopathic arthritis-associated uveitis. However, these patients may also experience an increased incidence of adverse and serious adverse events compared with those taking only methotrexate…

Insights into Precision Immunology for Research, RA & Infection

Lara C. Pullen, PhD  |  September 26, 2017

Research in precision immunology is in its early stages. But new insights into cohorts, RA gene expression and infection presented at FOCUS 2017 may benefit future research and patient care…

A Rose by Any Other Name: Why clinicians & patients prefer the term myalgic encephalomyelitis & other updates on chronic fatigue syndrome

Lara C. Pullen, PhD  |  September 26, 2017

A session at the FOCIS 2017 meeting examined the current challenges and understanding of chronic fatigue syndrome, also called myalgic encephalomyelitis, in the hope of stimulating new approaches to deciphering the disease’s mechanistic and immunological underpinnings…

AMP RA/Lupus Network Shares Its Progress

Lara C. Pullen, PhD  |  September 26, 2017

Researchers from the AMP RA/Lupus Network came together in June at the annual FOCIS meeting to share their progress as they perform a systematic molecular deconstruction of human diseases…

Acupuncture & Electrotherapy May Help Patients after Total Knee Arthroplasty

Lara C. Pullen, PhD  |  September 18, 2017

A new review examined how drug-free interventions affect pain relief and analgesic consumption for patients who have had knee surgery. Although little evidence shows these treatments reduce actual pain, electrotherapy and acupuncture may help patients delay their postoperative use of opioids…

Steroids May Increase Infection Risk in Patients with IgA Nephropathy

Lara C. Pullen, PhD  |  September 11, 2017

Treatment with oral methylprednisolone may be associated with an increased risk of serious adverse events, specifically infection, in patients with IgA nephropathy. Despite the five-times higher risk, study results also showed a three-times lower risk of kidney failure for the treatment group…

Hyaluronidase 2 May Play an Important Role in OA Progression

Lara C. Pullen, PhD  |  September 5, 2017

A new study in mice found that Hyal2 deficiency may play a role in the turnover of cartilage hyaluronan, resulting in an accumulation of hyaluronan and, eventually, the development of osteoarthritis. Researchers suspect these results indicate an imbalance in the metabolism of hyaluronan…

Tocilizumab Is Effective to Treat GCA

Lara C. Pullen, PhD  |  August 28, 2017

In a recent clinical trial, tocilizumab helped sustain glucocorticoid-free remission in patients with giant cell arteritis. Patients also received a prednisone taper, and 50% of tocilizumab-treated patients achieved prednisone-free remission and were less likely to experience disease flare compared with placebo…

Alendronate Decreases Hip Fracture Risk in Older Patients Using Oral Prednisolone

Lara C. Pullen, PhD  |  August 21, 2017

New research found that older patients on prednisolone who are also treated with alendronate experience a significantly lower risk of hip fracture. Alendronate use was also associated with a lower risk of death…

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