NEW YORK (Reuters Health)—Clinical outcomes of rheumatoid arthritis (RA) are similar with abatacept and tocilizumab treatment, but the factors that predict efficacy differ for the two agents. “The recommendations for RA treatment from the U.S. and EU describe the use of abatacept and tocilizumab as first-line biologics along with anti-TNF (anti-tumor necrosis factor) inhibitors,” Dr….
Articles by Natasha Yetman
Knee Replacement May ‘Turn Back the Clock’ for Arthritis Pain
(Reuters Health)—Knee replacement surgery may significantly ease pain and improve leg function and quality of life in patients with osteoarthritis or rheumatoid arthritis (RA), a new study suggests. While surgery doesn’t restore the same level of comfort and function patients had in their younger years, before they developed arthritis, the authors write in the journal…
GSK Shuts U.S. Plant Due to Bacteria
(Reuters)—Drugmaker GlaxoSmithKline temporarily closed a North Carolina factory on Tuesday after testing at a cooling tower found bacteria that causes deadly Legionnaire’s disease. The Legionella bacteria were discovered during routine inspections at the site in Zebulon, N.C., the company said. The shutdown is not expected to disrupt supplies of medicines made at the factory, which…
High-Risk Medical Devices Backed by Few Studies
(Reuters Health)—Many high-risk therapeutic devices get U.S. Food and Drug Administration (FDA) approval with only one study proving their safety and efficacy before going to market. Studies of how the devices work once they are on the market are also few and far between, according to a new study that looked at all 28 high-risk…
Rude Comments Damage Medical Team Performance
NEW YORK (Reuters Health)—Medical practitioners’ performance suffers when they are exposed to rudeness, new findings show. Neonatal intensive care unit (NICU) team members who heard disparaging comments while participating in a simulation exercise had lower diagnostic and procedural performance scores compared to team members who didn’t hear rude comments, Dr. Arieh Riskin, of Bnai-Zion Medical…
Short Time Between Pregnancies Linked to Osteoporosis
(Reuters Health)—Women who have pregnancies less than a year apart may have a greater risk for osteoporosis later in life than those who wait longer between babies, a study suggests. Researchers compared the reproductive histories of 239 postmenopausal women with osteoporosis to 298 similar women without thinning bones. Pregnancies no more than 12 months apart…
Biomarkers May Help Differentiate Crohn’s From Colitis
NEW YORK (Reuters Health)—Serum biomarkers can discriminate between Crohn’s disease (CD) and ulcerative colitis (UC), according to Danish and Dutch researchers. “The biomarker assays measure neo-epitopes, which are fragments of extracellular matrix protein degradation,” Joachim Høg Mortensen, a PhD student at Nordic Bioscience in Herlev, Denmark, told Reuters Health by email. “These neo-epitopes are increasingly…
China Gets Tougher for Western Drugmakers
LONDON (Reuters)—The Chinese market is getting tougher for Western pharmaceutical companies as Beijing bears down on a rising healthcare bill and prices come under pressure. The country, which has overtaken Japan as the world’s second largest market for prescription medicines after the U.S., has drawn major investment from global drugmakers in recent years — but…
Psoriatic Disease Linked to Higher Risk of Uveitis & Vice Versa
NEW YORK (Reuters Health)—Two classes of inflammatory diseases, uveitis and psoriatic disease, appear linked, as a diagnosis of one increases the risk of developing the other, new research has found. A study of Danish patient registries found nearly triple the rate of uveitis among patients with psoriatic arthritis compared to the general population, and double…
U.S. Hospitals Urge DOJ Antitrust Probe of Anthem-Cigna Deal
NEW YORK (Reuters)—U.S. hospitals urged antitrust regulators this week to consider whether health insurer Anthem Inc’s planned acquisition of rival Cigna Corp would boost healthcare costs. In a letter to the Department of Justice, the hospital industry’s largest lobbying group said combining the No. 1 and No. 5 health insurers threatens to reduce competition in…
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